Cyanidin Chloride inhibits ovariectomy‐induced osteoporosis by suppressing RANKL‐mediated osteoclastogenesis and associated signaling pathways
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26126
Abstract: Over‐production and activation of osteoclasts is a common feature of osteolytic conditions such as osteoporosis, tumor‐associated osteolysis, and inflammatory bone erosion. Cyanidin Chloride, a subclass of anthocyanin, displays antioxidant and anti‐carcinogenesis properties, but its role… read more here.
Keywords: chloride inhibits; rankl induced; ovariectomy induced; chloride ... See more keywords
Different regulatory roles of TNF-alpha and Il-6 in ovariectomy induced bone loss
Sign Up to like & getrecommendations! Published in 2018 at "Osteoarthritis and Cartilage"
DOI: 10.1016/j.joca.2018.02.191
Abstract: OARSI World Congress on Osteoarthritis - Promoting Clinical and Basic Research in Osteoarthritis, Liverpool, England, Apr 26-29, 2018 read more here.
Keywords: tnf alpha; ovariectomy induced; roles tnf; regulatory roles ... See more keywords
Tetrahydroberberine Prevents Ovariectomy-Induced Bone Loss by Inhibiting RANKL-Induced Osteoclastogenesis and Promoting Osteoclast Apoptosis.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.4c02982
Abstract: Postmenopausal osteoporosis (PMOP) arises from the disruption in bone remodeling caused by estrogen deficiency, leading to a heightened susceptibility to osteoporotic fractures in aging women. Tetrahydroberberine (THB) is a chemical compound extracted from Corydalis yanhusuo,… read more here.
Keywords: ovariectomy induced; induced bone; bone; bone loss ... See more keywords
Complement C3 deficiency inhibits osteoclast differentiation and prevents ovariectomy-induced osteoporosis.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of immunology"
DOI: 10.1093/jimmun/vkaf180
Abstract: The pathomechanistic role of the complement system is well recognized in various pathological conditions affecting bone tissues and the bone microenvironment, including rheumatoid arthritis, osteoarthritis, bone fractures, and periodontitis. The homeostasis of the bone is… read more here.
Keywords: differentiation; mice; induced osteoporosis; bone ... See more keywords
Gossypol Promotes Bone Formation in Ovariectomy-Induced Osteoporosis through Regulating Cell Apoptosis
Sign Up to like & getrecommendations! Published in 2018 at "BioMed Research International"
DOI: 10.1155/2018/3635485
Abstract: Osteoporosis is among the most common forms of age-related diseases, especially for females, which has been a grave public health problem. Drug therapies have shown promising outcomes to promote bone formation and bone density. This… read more here.
Keywords: bone formation; ovariectomy induced; induced osteoporosis; gossypol ... See more keywords
Ovariectomy-Induced Arterial Stiffening Differs From Vascular Aging and Is Reversed by GPER Activation
Sign Up to like & getrecommendations! Published in 2024 at "Hypertension"
DOI: 10.1161/hypertensionaha.123.22024
Abstract: BACKGROUND: Arterial stiffness is a cardiovascular risk factor and dramatically increases as women transition through menopause. The current study assessed whether a mouse model of menopause increases arterial stiffness in a similar manner to aging… read more here.
Keywords: arterial stiffening; ovariectomy; induced arterial; geometry ... See more keywords
25-Hydroxycholesterol-induced Osteoblast Oxiapoptophagy Is Involved in the Pathophysiological Process of Osteoporosis
Sign Up to like & getrecommendations! Published in 2023 at "In Vivo"
DOI: 10.21873/invivo.13069
Abstract: Abstract Background/Aim: 25-hydroxycholesterol (25-HC) plays important roles in lipid metabolism, inflammatory responses, and apoptosis, but its pathophysiological association with osteoporosis (OP) has not been verified in osteoblasts. Hence, we studied the pathophysiological linkage and underlying… read more here.
Keywords: ovariectomy induced; hydroxycholesterol induced; induced osteoblast; osteoporosis ... See more keywords
Effects of quercetin and vitamin E on ovariectomy-induced oxidative stress in rat serum and tibia
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Biological Sciences"
DOI: 10.2298/abs191115003v
Abstract: Paper description: Estrogen deficiency after ovariectomy induces an imbalance between the production of reactive oxygen species and the antioxidant defense system, leading to oxidative stress and resulting complications. Administration of either quercetin or vitamin E… read more here.
Keywords: tibia; ovariectomy induced; quercetin vitamin; oxidative stress ... See more keywords
Gallic acid inhibits osteoclastogenesis and prevents ovariectomy-induced bone loss
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.963237
Abstract: Osteoporosis is a common metabolic bone disease with a rapidly increasing prevalence, characterized by massive bone loss because of excessive osteoclast formation. Gallic acid (GA), a phenolic acid isolated from Cornus officinalis, has anti-inflammatory and… read more here.
Keywords: gallic acid; ovariectomy induced; bone; osteoclastogenesis ... See more keywords
Cinnamtannin B-1 Prevents Ovariectomy-Induced Osteoporosis via Attenuating Osteoclastogenesis and ROS Generation
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.01023
Abstract: Osteoporosis (OP) is one of the common bone metabolic diseases that endangers postmenopausal women and the elders. Both excessive bone resorption caused by osteoclast over-activation and increased oxidative stress are associated with osteoporosis. Cinnamtannin B-1… read more here.
Keywords: prevents ovariectomy; cinnamtannin prevents; osteoporosis via; ovariectomy induced ... See more keywords
Schisandrin B Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.01175
Abstract: Osteoporosis is a systemic skeletal disease which is highly prevalent worldwide and considered to be associated with excessive bone resorption mediated by osteoclast. Osteoclast differentiation is featured by the activation of inflammation-related pathways and the… read more here.
Keywords: induced bone; ovariectomy induced; bone loss; schisandrin inhibits ... See more keywords