Cyanidin Chloride inhibits ovariectomy‐induced osteoporosis by suppressing RANKL‐mediated osteoclastogenesis and associated signaling pathways
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26126
Abstract: Over‐production and activation of osteoclasts is a common feature of osteolytic conditions such as osteoporosis, tumor‐associated osteolysis, and inflammatory bone erosion. Cyanidin Chloride, a subclass of anthocyanin, displays antioxidant and anti‐carcinogenesis properties, but its role… read more here.
Keywords: chloride inhibits; rankl induced; ovariectomy induced; chloride ... See more keywords
Different regulatory roles of TNF-alpha and Il-6 in ovariectomy induced bone loss
Sign Up to like & getrecommendations! Published in 2018 at "Osteoarthritis and Cartilage"
DOI: 10.1016/j.joca.2018.02.191
Abstract: OARSI World Congress on Osteoarthritis - Promoting Clinical and Basic Research in Osteoarthritis, Liverpool, England, Apr 26-29, 2018 read more here.
Keywords: tnf alpha; ovariectomy induced; roles tnf; regulatory roles ... See more keywords
Gossypol Promotes Bone Formation in Ovariectomy-Induced Osteoporosis through Regulating Cell Apoptosis
Sign Up to like & getrecommendations! Published in 2018 at "BioMed Research International"
DOI: 10.1155/2018/3635485
Abstract: Osteoporosis is among the most common forms of age-related diseases, especially for females, which has been a grave public health problem. Drug therapies have shown promising outcomes to promote bone formation and bone density. This… read more here.
Keywords: bone formation; ovariectomy induced; induced osteoporosis; gossypol ... See more keywords
25-Hydroxycholesterol-induced Osteoblast Oxiapoptophagy Is Involved in the Pathophysiological Process of Osteoporosis
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DOI: 10.21873/invivo.13069
Abstract: Abstract Background/Aim: 25-hydroxycholesterol (25-HC) plays important roles in lipid metabolism, inflammatory responses, and apoptosis, but its pathophysiological association with osteoporosis (OP) has not been verified in osteoblasts. Hence, we studied the pathophysiological linkage and underlying… read more here.
Keywords: ovariectomy induced; hydroxycholesterol induced; induced osteoblast; osteoporosis ... See more keywords
Effects of quercetin and vitamin E on ovariectomy-induced oxidative stress in rat serum and tibia
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Biological Sciences"
DOI: 10.2298/abs191115003v
Abstract: Paper description: Estrogen deficiency after ovariectomy induces an imbalance between the production of reactive oxygen species and the antioxidant defense system, leading to oxidative stress and resulting complications. Administration of either quercetin or vitamin E… read more here.
Keywords: tibia; ovariectomy induced; quercetin vitamin; oxidative stress ... See more keywords
Gallic acid inhibits osteoclastogenesis and prevents ovariectomy-induced bone loss
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.963237
Abstract: Osteoporosis is a common metabolic bone disease with a rapidly increasing prevalence, characterized by massive bone loss because of excessive osteoclast formation. Gallic acid (GA), a phenolic acid isolated from Cornus officinalis, has anti-inflammatory and… read more here.
Keywords: gallic acid; ovariectomy induced; bone; osteoclastogenesis ... See more keywords
Cinnamtannin B-1 Prevents Ovariectomy-Induced Osteoporosis via Attenuating Osteoclastogenesis and ROS Generation
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.01023
Abstract: Osteoporosis (OP) is one of the common bone metabolic diseases that endangers postmenopausal women and the elders. Both excessive bone resorption caused by osteoclast over-activation and increased oxidative stress are associated with osteoporosis. Cinnamtannin B-1… read more here.
Keywords: prevents ovariectomy; cinnamtannin prevents; osteoporosis via; ovariectomy induced ... See more keywords
Schisandrin B Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.01175
Abstract: Osteoporosis is a systemic skeletal disease which is highly prevalent worldwide and considered to be associated with excessive bone resorption mediated by osteoclast. Osteoclast differentiation is featured by the activation of inflammation-related pathways and the… read more here.
Keywords: induced bone; ovariectomy induced; bone loss; schisandrin inhibits ... See more keywords
Pristimerin Suppresses RANKL-Induced Osteoclastogenesis and Ameliorates Ovariectomy-Induced Bone Loss
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.621110
Abstract: Osteoporosis is characterized by bone loss and destruction of trabecular architecture, which greatly increases the burden on the healthcare system. Excessive activation of osteoclasts is an important cause of osteoporosis, and suppression of osteoclastogenesis is… read more here.
Keywords: rankl induced; ovariectomy induced; bone loss; osteoclastogenesis ... See more keywords
6′-O-Galloylpaeoniflorin Attenuates Osteoclasto-genesis and Relieves Ovariectomy-Induced Osteoporosis by Inhibiting Reactive Oxygen Species and MAPKs/c-Fos/NFATc1 Signaling Pathway
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.641277
Abstract: Emerging evidence suggests bright prospects of some natural antioxidants in the treatment of osteoporosis. 6′-O-Galloylpaeoniflorin (GPF), an antioxidant isolated from peony roots (one of very widely used Oriental medicines, with various anti-inflammatory, antitumor, and antioxidant… read more here.
Keywords: reactive oxygen; signaling pathway; ovariectomy induced; gpf ... See more keywords
Berbamine inhibits RANKL- and M-CSF-mediated osteoclastogenesis and alleviates ovariectomy-induced bone loss
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1032866
Abstract: Osteoporosis is a common public health problem characterized by decreased bone mass, increased bone brittleness and damage to the bone microstructure. Excessive bone resorption by osteoclasts is the main target of the currently used drugs… read more here.
Keywords: ovariectomy induced; bone; osteoporosis; bone loss ... See more keywords