Articles with "ovary cells" as a keyword



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Validation and identification of reference genes in Chinese hamster ovary cells for Fc-fusion protein production

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Published in 2020 at "Experimental Biology and Medicine"

DOI: 10.1177/1535370220914058

Abstract: Chinese hamster ovary cells are the predominant cell lines used for bio-therapeutic production. Real-time quantitative PCR (RT-qPCR) and transcriptomics are powerful tools to understand and optimize the Chinese hamster ovary cells for higher productivity or… read more here.

Keywords: hamster ovary; chinese hamster; reference genes; ovary cells ... See more keywords
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Enrichment of microsomes from Chinese hamster ovary cells by subcellular fractionation for its use in proteomic analysis

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Published in 2020 at "PLoS ONE"

DOI: 10.1371/journal.pone.0237930

Abstract: Chinese hamster ovary cells have been the workhorse for the production of recombinant proteins in mammalian cells. Since biochemical, cellular and omics studies are usually affected by the lack of suitable fractionation procedures to isolate… read more here.

Keywords: ovary cells; enriched fractions; fractionation; hamster ovary ... See more keywords