Dynamic metabolic network modeling of mammalian Chinese hamster ovary (CHO) cell cultures with continuous phase kinetics transitions
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical Engineering Journal"
DOI: 10.1016/j.bej.2018.11.015
Abstract: Abstract Cellular biological environments are difficult to analyse on the first principle basis. In this modeling work, a novel approach is presented which transits from a broad mechanistic description of the individual metabolic pathways to… read more here.
Keywords: metabolic network; chinese hamster; cell; ovary cho ... See more keywords
Characterization of dynamic regulation in Chinese hamster ovary (CHO) cell cultures in the late exponential phase
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical Engineering Journal"
DOI: 10.1016/j.bej.2020.107897
Abstract: Abstract Chinese hamster ovary (CHO) cells are the most commonly used host cells to produce biologics in the biopharmaceutical industry. In a batch or fed-batch process, cells grow at a relatively constant rate at the… read more here.
Keywords: phase; ovary cho; hamster ovary; chinese hamster ... See more keywords