Vascular measures of atherosclerosis in detrusor overactivity and controls
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DOI: 10.1002/nau.23784
Abstract: The mechanisms leading to the development of detrusor overactivity (DO) are still relatively poorly understood, however, animal studies suggest that atherosclerosis and reduced blood flow to the bladder may be one etiological pathway. Thus, the… read more here.
Keywords: vascular measures; measures atherosclerosis; overactivity; detrusor overactivity ... See more keywords
Inhibition of Renin-Angiotensin System from Conception to Young Mature Life Induces Salt-Sensitive Hypertension via Angiotensin II-Induced Sympathetic Overactivity in Adult Male Rats.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-8023-5_5
Abstract: Previous studies indicate that perinatal compromise of taurine causes cardiovascular disorders in adults via the influence of taurine on renin-angiotensin system (RAS). This study tested whether perinatal inhibition of the RAS would itself alter the… read more here.
Keywords: adult; system; water; angiotensin ... See more keywords
Efficacy and Safety of AbobotulinumtoxinA in Patients with Neurogenic Detrusor Overactivity Incontinence Performing Regular Clean Intermittent Catheterization: Pooled Results from Two Phase 3 Randomized Studies (CONTENT1 and CONTENT2).
Sign Up to like & getrecommendations! Published in 2022 at "European urology"
DOI: 10.1016/j.eururo.2022.03.010
Abstract: BACKGROUND For patients with neurogenic detrusor overactivity incontinence (NDOI), treatment with oral medications is often unsatisfactory. OBJECTIVE To assess the efficacy and safety of abobotulinumtoxinA (aboBoNT-A) for NDOI. DESIGN, SETTING, AND PARTICIPANTS Two randomized, double-blind… read more here.
Keywords: abobotulinumtoxina; placebo; overactivity; detrusor ... See more keywords
Endothelial overactivity maybe a contributing factor in athletes with vasovagal syncope.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2016.11.272
Abstract: Article history: Received 5 November 2016 Accepted 14 November 2016 Available online xxxx FMD [4]. Santini et al. [4] showed that vascular hyperreactivity in response to nitrate administration is particularly overt in vasodepressive syncope. In… read more here.
Keywords: endothelial overactivity; factor athletes; contributing factor; maybe contributing ... See more keywords
Effect of arousal on sympathetic overactivity in patients with obstructive sleep apnea.
Sign Up to like & getrecommendations! Published in 2019 at "Sleep medicine"
DOI: 10.1016/j.sleep.2019.01.044
Abstract: OBJECTIVE Obstructive sleep apnea (OSA) is associated with sympathetic overactivity. Intermittent hypoxemia and repetitive arousals are the proposed mechanisms; however, the main contributing factor for sympathetic overactivity remains to be determined. We therefore investigated the… read more here.
Keywords: sleep apnea; overactivity; obstructive sleep; analysis ... See more keywords
Cold stress‐induced bladder overactivity in type 2 diabetic mellitus rats is mitigated by the combination of a M3‐muscarinic antagonist and a β3‐adrenergic agonist
Sign Up to like & getrecommendations! Published in 2022 at "LUTS: Lower Urinary Tract Symptoms"
DOI: 10.1111/luts.12472
Abstract: Goto‐Kakizaki (GK) rats with type 2 diabetes mellitus respond to low temperature (LT) environments with bladder overactivity, including increased voiding frequency and decreased voiding interval and micturition volume. We determined if bladder overactivity could be… read more here.
Keywords: antagonist adrenergic; bladder overactivity; combination muscarinic; overactivity ... See more keywords
Enhanced RAGE Expression and Excess Reactive-Oxygen Species Production Mediates Rho Kinase-Dependent Detrusor Overactivity After Methylglyoxal Exposure
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DOI: 10.3389/fphys.2022.860342
Abstract: Methylglyoxal (MGO) is a highly reactive dicarbonyl compound implicated in diabetes-associated diseases. In vascular tissues, MGO induces the formation of advanced glycation end products (AGEs) that bounds its receptor RAGE, initiating the downstream tissue injury.… read more here.
Keywords: reactive oxygen; bladder; rho kinase; overactivity ... See more keywords
Effects of Acute Sacral Neuromodulation at Different Frequencies on Bladder Overactivity in Pigs
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DOI: 10.5213/inj.1732754.377
Abstract: Purpose We investigated the effects of different stimulation frequencies on the inhibition of bladder overactivity by sacral neuromodulation (SNM) in pigs. Methods Implant-driven stimulators were used to stimulate the S3 spinal nerve in 13 pigs.… read more here.
Keywords: different frequencies; snm; overactivity; bladder overactivity ... See more keywords