Association of Immunotherapy With Survival Among Patients With Brain Metastases Whose Cancer Was Managed With Definitive Surgery of the Primary Tumor
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.15444
Abstract: Key Points Question Is combining immunotherapy with other cancer treatments associated with improved overall survival in patients with brain metastases? Findings In this comparative effectiveness study of 3112 adult patients who received definitive surgery of… read more here.
Keywords: improved overall; immunotherapy; associated improved; cancer ... See more keywords
Association of Race/Ethnicity With Overall Survival Among Patients With Colorectal Liver Metastasis
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DOI: 10.1001/jamanetworkopen.2020.16019
Abstract: This cohort study assesses the association of race/ethnicity with overall survival among patients with colorectal liver metastasis overall and among those undergoing liver resection. read more here.
Keywords: ethnicity overall; association race; among patients; survival among ... See more keywords
Association of Neoadjuvant Chemotherapy With Overall Survival in Women With Metastatic Endometrial Cancer
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DOI: 10.1001/jamanetworkopen.2020.28612
Abstract: This cohort study uses data from the National Cancer Database to investigate the association of neoadjuvant therapy with overall survival in women with metastatic endometrial cancer. read more here.
Keywords: association neoadjuvant; survival women; metastatic endometrial; cancer ... See more keywords
Correlation Between Surrogate End Points and Overall Survival in a Multi-institutional Clinicogenomic Cohort of Patients With Non–Small Cell Lung or Colorectal Cancer
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DOI: 10.1001/jamanetworkopen.2021.17547
Abstract: Key Points Question What surrogate end point for capturing worsening disease is most correlated with overall survival (OS) in large linked clinicogenomic data sets? Findings In this cohort study of patients with non–small cell lung… read more here.
Keywords: overall survival; end; patients non; non small ... See more keywords
Epidemiologic Trends of and Factors Associated With Overall Survival for Patients With Gastroenteropancreatic Neuroendocrine Tumors in the United States
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DOI: 10.1001/jamanetworkopen.2021.24750
Abstract: Key Points Question What are the epidemiologic trends of and prognostic factors for gastroenteropancreatic neuroendocrine tumors (GEP-NETs) in patients in the US? Findings In this cohort study of 43 751 patients with GEP-NETs, most cases occurred… read more here.
Keywords: neuroendocrine tumors; associated overall; gastroenteropancreatic neuroendocrine; overall survival ... See more keywords
Association Between Smoking History and Overall Survival in Patients Receiving Pembrolizumab for First-Line Treatment of Advanced Non–Small Cell Lung Cancer
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DOI: 10.1001/jamanetworkopen.2022.14046
Abstract: This cohort study compares the overall survival between patients who currently or formerly smoked with patients who never smoked and initiated pembrolizumab monotherapy as first-line treatment for advanced non–small lung cancer. read more here.
Keywords: first line; treatment advanced; overall survival; line treatment ... See more keywords
Use of First-Line Immune Checkpoint Inhibitors and Association With Overall Survival Among Patients With Metastatic Melanoma in the Anti–PD-1 Era
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DOI: 10.1001/jamanetworkopen.2022.25459
Abstract: Key Points Question Following the US Food and Drug Administration’s approval of PD-1 immune checkpoint inhibitors (ICI) for metastatic melanoma, what were the utilization and overall survival associated with ICI in the first-line setting after… read more here.
Keywords: first line; overall survival; line; metastatic melanoma ... See more keywords
Overall Survival Benefits of Cancer Drugs Approved in China From 2005 to 2020
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DOI: 10.1001/jamanetworkopen.2022.25973
Abstract: Key Points Question What is the overall survival benefit of cancer drugs approved in China between 2005 and 2020? Findings In this mixed-methods study comprising a systematic review and cross-sectional analysis of 78 cancer drugs… read more here.
Keywords: cancer; cancer drugs; drugs approved; approved china ... See more keywords
Transportability of Overall Survival Estimates From US to Canadian Patients With Advanced Non–Small Cell Lung Cancer With Implications for Regulatory and Health Technology Assessment
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DOI: 10.1001/jamanetworkopen.2022.39874
Abstract: Key Points Question Is overall survival of patients with advanced non–small cell lung cancer (NSCLC) that is estimated from US-based clinical practice data externally valid among Canadian patients who receive the same systemic therapies? Findings… read more here.
Keywords: non small; survival; patients advanced; small cell ... See more keywords
Association of Low-Fat Dietary Pattern With Breast Cancer Overall Survival: A Secondary Analysis of the Women’s Health Initiative Randomized Clinical Trial
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DOI: 10.1001/jamaoncol.2018.1212
Abstract: Importance In a randomized clinical trial, a low-fat eating pattern was associated with lower risk of death after breast cancer. However, the extent to which results were driven by dietary influence on survival after breast… read more here.
Keywords: cancer overall; group; breast cancer; cancer ... See more keywords
Association of Patient Sex With Efficacy of Immune Checkpoint Inhibitors and Overall Survival in Advanced Cancers: A Systematic Review and Meta-analysis
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DOI: 10.1001/jamaoncol.2018.5904
Abstract: Importance Sex-associated differences in immune response are known, but a meta-analysis suggested men, compared with women, derive greater value from immunotherapy for advanced solid-organ malignant neoplasms. However, methodologic concerns and subsequent trials have placed these… read more here.
Keywords: immunotherapy; patient sex; sex; overall survival ... See more keywords