Abstract CN05-02: Next generation strategies to overcome adaptive resistance to MAPK-directed therapies
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.targ-19-cn05-02
Abstract: Adaptive resistance remains a major challenge limiting the clinical effectiveness of inhibitors of oncogenic MAPK signaling (RAF and MEK inhibitors), there is thus a pressing need for compounds and combinatorial strategies that would potently and… read more here.
Keywords: overcome adaptive; resistance; ras activation; adaptive resistance ... See more keywords