Articles with "overcome failures" as a keyword



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Strategies to Overcome Failures in T-Cell Immunotherapies by Targeting PI3K-δ and –γ

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Published in 2021 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2021.718621

Abstract: PI3K-δ and PI3K-γ are critical regulators of T-cell differentiation, senescence, and metabolism. PI3K-δ and PI3K-γ signaling can contribute to T-cell inhibition via intrinsic mechanisms and regulation of suppressor cell populations, including regulatory T-cells and myeloid… read more here.

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