Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade
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DOI: 10.1038/s41586-018-0768-9
Abstract: Most patients with cancer either do not respond to immune checkpoint blockade or develop resistance to it, often because of acquired mutations that impair antigen presentation. Here we show that loss of function of the… read more here.
Keywords: checkpoint blockade; resistance; overcomes resistance; adar1 ... See more keywords