Overcoming biological barriers to improve solid tumor immunotherapy.
Sign Up to like & getrecommendations! Published in 2021 at "Drug delivery and translational research"
DOI: 10.1007/s13346-021-00923-8
Abstract: Cancer immunotherapy has been at the forefront of therapeutic interventions for many different tumor types over the last decade. While the discovery of immunotherapeutics continues to occur at an accelerated rate, their translation is often… read more here.
Keywords: tumor immunotherapy; tumor; biological barriers; solid tumor ... See more keywords
Biotechnology: Overcoming biological barriers to nucleic acid delivery using lipid nanoparticles
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Biology"
DOI: 10.1371/journal.pbio.3002105
Abstract: The promise of therapeutic nucleic acids has long been tempered by difficulty in overcoming biological barriers to their delivery. The past two decades have seen the development of ionizable lipid nanoparticles as a vehicle for… read more here.
Keywords: overcoming biological; delivery; nucleic acid; biological barriers ... See more keywords
Delivering Therapeutics to Glioblastoma: Overcoming Biological Constraints
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23031711
Abstract: Glioblastoma multiforme is the most lethal intrinsic brain tumor. Even with the existing treatment regimen of surgery, radiation, and chemotherapy, the median survival time is only 15–23 months. The invasive nature of this tumor makes… read more here.
Keywords: overcoming biological; therapeutics glioblastoma; glioblastoma overcoming; delivering therapeutics ... See more keywords