Abstract 5833: Overcoming immune anergy by targeting tumor macrophages: Rearranging the tumor microenvironment
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-5833
Abstract: There are remarkable advances in immunotherapy which have transformed solid tumor therapy outcomes for many patients. Immunotherapy rationales include checkpoint inhibitor monoclonal antibodies (CIMA) or chimeric antigen receptor T cell therapy that have become primary… read more here.
Keywords: anergy targeting; immune anergy; tumor; overcoming immune ... See more keywords
Self-delivery photothermal-boosted-nanobike multi-overcoming immune escape by photothermal/chemical/immune synergistic therapy against HCC
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DOI: 10.1186/s12951-024-02399-3
Abstract: Immune checkpoint inhibitors (ICIs) combined with antiangiogenic therapy have shown encouraging clinical benefits for the treatment of unresectable or metastatic hepatocellular carcinoma (HCC). Nevertheless, therapeutic efficacy and wide clinical applicability remain a challenge due to… read more here.
Keywords: multi overcoming; therapy; hcc; immune escape ... See more keywords
Overcoming Immune Therapy Resistance in Cancer Through Innate Immune Reprogramming
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DOI: 10.3390/ijms26199554
Abstract: Overcoming immune resistance remains the critical barrier to durable immunotherapy responses. Tumors with non-inflamed, “cold” microenvironments exclude cytotoxic lymphocytes and evade checkpoint blockade. Innate nucleic acid-sensing pathways—including TLRs, RIG-I-like RNA sensors, and the cGAS–STING DNA-sensing… read more here.
Keywords: immune reprogramming; immune therapy; overcoming immune; therapy resistance ... See more keywords
Overcoming Immune Deficiency with Allogrooming
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DOI: 10.3390/insects14020128
Abstract: Simple Summary We investigated whether two closely related termite species differ in their reliance on social or individual immunity against two species of pathogenic fungi, which were all collected from the same location. Our results… read more here.
Keywords: insects; immunity; immune deficiency; deficiency allogrooming ... See more keywords