Phenformin inhibits growth and epithelial-mesenchymal transition of ErbB2-overexpressing breast cancer cells through targeting the IGF1R pathway.
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DOI: 10.18632/oncotarget.19466
Abstract: Reports suggest that metformin, a popular anti-diabetes drug, prevents breast cancer through various systemic effects, including insulin-like growth factor receptor (IGFR) regulation. Although the anti-cancer properties of metformin have been well-studied, reports on a more… read more here.
Keywords: overexpressing breast; erbb2 overexpressing; breast cancer; phenformin ... See more keywords