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Strain Typing of Classical Scrapie and Bovine Spongiform Encephalopathy (BSE) by Using Ovine PrP (ARQ/ARQ) Overexpressing Transgenic Mice

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23126744

Abstract: Transmissible spongiform encephalopathies (TSE), caused by abnormal prion protein (PrPSc), affect many species. The most classical scrapie isolates harbor mixtures of strains in different proportions. While the characterization of isolates has evolved from using wild-type… read more here.

Keywords: arq; transgenic mice; ovine prp; mice ... See more keywords