Overexpression of Global Regulator SCrp Leads to the Discovery of New Angucyclines in Streptomyces sp. XS-16
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DOI: 10.3390/md21040240
Abstract: Six angucyclines including three unreported compounds (1–3) were isolated from Streptomyces sp. XS-16 by overexpressing the native global regulator of SCrp (cyclic AMP receptor). The structures were characterized based on nuclear magnetic resonance (NMR) and… read more here.
Keywords: regulator scrp; scrp leads; leads discovery; global regulator ... See more keywords