Overexpression of Gremlin 1 by sonic hedgehog signaling promotes pancreatic cancer progression
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Oncology"
DOI: 10.3892/ijo.2018.4573
Abstract: Sonic hedgehog (SHH) signaling is an important promotor of desmoplasia, a critical feature in pancreatic cancer stromal reactions involving the activation of pancreatic stellate cells (PSCs). Gremlin 1 is widely overexpressed in cancer-associated stromal cells,… read more here.
Keywords: overexpression gremlin; pancreatic cancer; expression; shh ... See more keywords