Study of the influence of NGF-β gene overexpression in human mesenchymal stem cells on the expression level of SOX1 and neural pathway genes.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular biology reports"
DOI: 10.1007/s11033-022-07283-7
Abstract: BACKGROUND Nerve growth factor (NGF) is a protein exhibiting an influence on the neural development and also, its' impact on the stem cells remains a great potential treatment strategy. The influence of its overexpression on… read more here.
Keywords: influence; overexpression human; neural pathway; stem ... See more keywords
Neonatal Lethality and Inflammatory Phenotype of the New Transgenic Mice with Overexpression of Human Interleukin-6 in Myeloid Cells
Sign Up to like & getrecommendations! Published in 2018 at "Doklady Biochemistry and Biophysics"
DOI: 10.1134/s1607672918060157
Abstract: To model human interleukin-6 (hIL-6) associated diseases, unique mice with transgenic overexpression of human IL-6 and reporter fluorescent protein EGFP in cells of macrophage-monocyte lineage were generated using loxP–Cre system. High level of hIL-6 production… read more here.
Keywords: overexpression; human interleukin; mice; neonatal lethality ... See more keywords
Inhibition of glioblastoma cell invasion by hsa-miR-145-5p and hsa-miR-31-5p co-overexpression in human mesenchymal stem cells.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of neurosurgery"
DOI: 10.3171/2017.8.jns1788
Abstract: In BriefThe authors demonstrated that hsa-miR-145-5p and -31-5p overexpression in human bone marrow-derived mesenchymal stem cells (hMSCs) inhibited the invasion of glioma cells via contact-dependent transfer. It is already known that some miRNAs suppress the… read more here.
Keywords: mir 145; hsa mir; hsa; overexpression human ... See more keywords