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   Articles with "overexpression mir" as a keyword



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Overexpression of miR‐301a‐3p promotes colorectal cancer cell proliferation and metastasis by targeting deleted in liver cancer‐1 and runt‐related transcription factor 3

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recommendations! Published in 2019 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.27894

Abstract: Colorectal cancer (CRC) is the third most common type of cancer. MicroRNAs have been reported to participate in the progression of various cancers. In previous studies, miR‐301a‐3p expression was shown to be upregulated in CRC… read more here.

Keywords: mir 301a; overexpression mir; cell proliferation; cancer ... See more keywords
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Overexpression of miR-183/-96/-182 triggers neuronal cell fate in Human Retinal Pigment Epithelial (hRPE) cells in culture.

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recommendations! Published in 2017 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2016.12.071

Abstract: miR-183 cluster, composed of miR-183/-96/-182 genes, is highly expressed in the adult retina, particularly in photoreceptors. It involves in development, maturation and normal function of neuroretina. Ectopic overexpression of miR-183/-96/-182 genes was performed to assess… read more here.

Keywords: mir 183; 183 182; hrpe cells; overexpression mir ... See more keywords
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Overexpression of miR-335 inhibits the migration and invasion of osteosarcoma by targeting SNIP1.

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recommendations! Published in 2019 at "International journal of biological macromolecules"

DOI: 10.1016/j.ijbiomac.2019.04.016

Abstract: MicroRNAs (miRNAs) are key regulators in the development and progression of osteosarcoma (OS). Based on our previous microarray data, we found that miR-335 expression was downregulated in OS tissue relative to normal tissue. Herein, we… read more here.

Keywords: overexpression mir; snip1; invasion; migration ... See more keywords
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MicroRNA‐93 alleviates neuropathic pain through targeting signal transducer and activator of transcription 3

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recommendations! Published in 2017 at "International Immunopharmacology"

DOI: 10.1016/j.intimp.2017.01.027

Abstract: Abstract Emerging evidence suggests that microRNAs (miRNAs) play a critical role in the pathogenesis of neuropathic pain. However, the exact role of miRNAs in regulating neuropathic pain remains largely unknown. In this study, we aimed… read more here.

Keywords: overexpression mir; signal transducer; neuropathic pain; cci rats ... See more keywords
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Overexpression of miR-133a-3p inhibits fibrosis and proliferation of keloid fibroblasts by regulating IRF5 to inhibit the TGF-β/Smad2 pathway.

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recommendations! Published in 2020 at "Molecular and cellular probes"

DOI: 10.1016/j.mcp.2020.101563

Abstract: AIM Keloid is a benign dermal tumor with excessive hyperplasia and deposition of collagen. As a common tumor suppressor gene, miR-133a-3p has not been studied in keloid. This study will delve into the specific mechanism… read more here.

Keywords: overexpression mir; fibrosis; keloid; proliferation ... See more keywords
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Overexpression of miR-669m inhibits erythroblast differentiation

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recommendations! Published in 2020 at "Scientific Reports"

DOI: 10.1038/s41598-020-70442-y

Abstract: MicroRNAs (miRNAs), one of small non-coding RNAs, regulate many cell functions through their post-transcriptionally downregulation of target genes. Accumulated studies have revealed that miRNAs are involved in hematopoiesis. In the present study, we investigated effects… read more here.

Keywords: overexpression mir; overexpression; 669m inhibits; differentiation ... See more keywords
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Overexpression of miR-331 Indicates Poor Prognosis and Promotes Progression of Breast Cancer

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recommendations! Published in 2020 at "Oncology Research and Treatment"

DOI: 10.1159/000508792

Abstract: Background: With the increasing number of cases of breast cancer every year, the exploration of novel biomarkers has drawn attention. miR-331 has been demonstrated to play a role in various cancers, but its role in… read more here.

Keywords: overexpression mir; mir 331; prognosis; breast cancer ... See more keywords
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Overexpression of miR-26b decreases the cisplatin-resistance in laryngeal cancer by targeting ATF2

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recommendations! Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.20784

Abstract: Cisplatin is a common used chemotherapeutic drug for the treatment of laryngeal cancer. However, drug-resistance is a major obstacle in platinum-based chemotherapy for laryngeal cancer. Recent studies have demonstrated that dysregulation of microRNAs (miRNAs) is… read more here.

Keywords: overexpression mir; laryngeal cancer; cisplatin; mir 26b ... See more keywords
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Overexpression of miR-148a-3p inhibits extracellular matrix degradation and alleviates IL-1β-induced intervertebral disc degeneration

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recommendations! Published in 2023 at "Iranian Journal of Basic Medical Sciences"

DOI: 10.22038/ijbms.2022.64645.14228

Abstract: Objective(s): Recently, studies on microRNAs (miRNAs) and their targets and related genes have provided new therapeutic opportunities for controlling intervertebral disc degeneration (IDD). We aimed to investigate the effects of miR-148a-3p overexpression on IDD progression.… read more here.

Keywords: overexpression mir; disc degeneration; mir 148a; intervertebral disc ... See more keywords
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Overexpression of miR-30c-5p reduces cellular cytotoxicity and inhibits the formation of kidney stones through ATG5

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recommendations! Published in 2019 at "International Journal of Molecular Medicine"

DOI: 10.3892/ijmm.2019.4440

Abstract: MicroRNAs (miRNAs or miRs) are critical regulators in various diseases. In the current study, the role of miR-30c-5p in the formation of sodium oxalate-induced kidney stones was investigated. For this purpose, human renal tubular epithelial… read more here.

Keywords: overexpression mir; sodium oxalate; mir 30c; cell ... See more keywords
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Lentivirus-mediated overexpression of miR-124 suppresses growth and invasion by targeting JAG1 and EZH2 in gastric cancer.

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recommendations! Published in 2018 at "Oncology letters"

DOI: 10.3892/ol.2018.8194

Abstract: MicroRNA-124 (miR-124) expression is downregulated and has a tumor suppressor role in various types of cancer. The present study revealed that genes encoding miR-124 were frequently methylated and the expression of miR-124 was downregulated in… read more here.

Keywords: overexpression mir; gastric cancer; jag1; cancer ... See more keywords