Systemic lupus erythematosus overlapping dermatomyositis owing to a heterozygous TREX1 Asp130Asn missense mutation.
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DOI: 10.1016/j.clim.2021.108732
Abstract: The 3' repair exonuclease 1 (TREX1) gene encodes a nuclear protein with 3' exonuclease activity, and the mutations have been associated with autoimmune diseases. Herein, we performed genetic analysis for the TREX1 gene in 55… read more here.
Keywords: trex1; systemic lupus; overlapping dermatomyositis; lupus erythematosus ... See more keywords