Deciphering the scalene association among type‐2 diabetes mellitus, prostate cancer, and chronic myeloid leukemia via enrichment analysis of disease‐gene network
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DOI: 10.1002/cam4.1845
Abstract: The potential biological relationship between type‐2 diabetes mellitus (T2DM) has been focused in numerous studies. To investigate the molecular associations among T2DM, prostate cancer (PCa), and chronic myeloid leukemia (CML), using a biomolecular network enrichment… read more here.
Keywords: enrichment analysis; cml pca; overlapping genes; pca ... See more keywords
Three Novel Antisense Overlapping Genes in E. coli O157:H7 EDL933
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DOI: 10.1128/spectrum.02351-22
Abstract: The abundance of long overlapping genes in prokaryotic genomes is likely to be significantly underestimated, since such genes are not allowed in genome annotations. However, ribosome profiling catches mRNA in the moment of being template… read more here.
Keywords: o157 edl933; abundance long; coli o157; overlapping genes ... See more keywords
Airway transcriptomic profiling after bronchial thermoplasty
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DOI: 10.1183/23120541.00123-2018
Abstract: Background Bronchial thermoplasty is a nonpharmacological, device-based treatment option for a specific population of severe asthmatic subjects, but the underlying mechanisms are largely unknown. The purpose of this study is to identify potential altered pathways… read more here.
Keywords: asthmatic subjects; airway transcriptomic; overlapping genes; thermoplasty ... See more keywords
Overlapping genes and the proteins they encode differ significantly in their sequence composition from non-overlapping genes
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DOI: 10.1371/journal.pone.0202513
Abstract: Overlapping genes represent a fascinating evolutionary puzzle, since they encode two functionally unrelated proteins from the same DNA sequence. They originate by a mechanism of overprinting, in which point mutations in an existing frame allow… read more here.
Keywords: proteins encode; differ significantly; overlapping genes; genes proteins ... See more keywords
Constrained evolution of overlapping genes in viral host adaptation: Acquisition of glycosylation motifs in hepadnaviral precore/core genes
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DOI: 10.1371/journal.ppat.1010739
Abstract: Hepadnaviruses use extensively overlapping genes to expand their coding capacity, especially the precore/core genes encode the precore and core proteins with mostly identical sequences but distinct functions. The precore protein of the woodchuck hepatitis virus… read more here.
Keywords: core genes; overlapping genes; glycosylation; precore core ... See more keywords
Overlapping genes connect rheumatoid arthritis and head and neck cancer: coincidence or shared immune pathophysiology?
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2025.1578016
Abstract: Introduction Despite advances in understanding the pathophysiology of rheumatoid arthritis (RA) and head and neck cancer (HNC) individually, their shared genetic and molecular mechanisms remain poorly defined. Methods This study aimed to explore gene-level connections… read more here.
Keywords: head neck; arthritis head; overlapping genes; pathophysiology ... See more keywords