Near Infrared-Activatable Nanomodulator Enabling Self-Amplifying Calcium Overload and Oxidative Stress for Precision Cancer Therapy.
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DOI: 10.1002/adhm.202503914
Abstract: Calcium interference therapy (CIT) is a promising cancer therapeutic strategy, but its efficacy is limited by intrinsic cellular calcium regulation. To address this limitation, herein, a near-infrared (NIR)-responsive nanoplatform, UC@COFs@CaO2-HA/PAG/ICG (UCCPI), integrating dual-amplified CIT with… read more here.
Keywords: cancer; calcium overload; therapy; overload oxidative ... See more keywords
Effects of Iron Overload and Oxidative Damage on the Musculoskeletal System in the Space Environment: Data from Spaceflights and Ground-Based Simulation Models
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DOI: 10.3390/ijms19092608
Abstract: The space environment chiefly includes microgravity and radiation, which seriously threatens the health of astronauts. Bone loss and muscle atrophy are the two most significant changes in mammals after long-term residency in space. In this… read more here.
Keywords: overload oxidative; space; oxidative damage; space environment ... See more keywords