Gushukang exerts osteopreserve effects by regulating vitamin D and calcium metabolism in ovariectomized mice
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Bone and Mineral Metabolism"
DOI: 10.1007/s00774-018-0924-1
Abstract: Calcium homeostasis plays vital roles in the management of bone health. Traditional herbal formula Gushukang (GSK) was clinically applied to treat primary osteoporosis. This study aimed to explore the osteoprotective effects of GSK and its… read more here.
Keywords: ovx mice; bone; mice; calcium ... See more keywords
RAMP3 deficiency enhances postmenopausal obesity and metabolic disorders
Sign Up to like & getrecommendations! Published in 2018 at "Peptides"
DOI: 10.1016/j.peptides.2018.10.006
Abstract: &NA; There is a marked increase in the incidence of visceral adiposity and insulin resistance among women following menopause. Adrenomedullin (AM) is an endogenous peptide first identified as a vasodilator, but now known to exert… read more here.
Keywords: ramp3 ovx; ovx mice; ramp3; postmenopausal obesity ... See more keywords
Urethral proteomic analysis in ovariectomized mice administered 17β-oestradiol replacement therapy
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Obstetrics and Gynaecology"
DOI: 10.1080/01443615.2017.1292225
Abstract: Abstract The molecular mechanism by which 17β-oestradiol (E2) increases urethral tone is unclear. As human tissue is limited in availability, we explored changes in the urethras of ovariectomized (OVX) mice. Twenty-four virgin female mice were… read more here.
Keywords: replacement; ovx mice; tone; ovariectomized mice ... See more keywords
The effects of standard and soy-free chow on cerebral artery function in ovariectomized female mice
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5731987
Abstract: As females age, they transition through menopause, experiencing a decrease in estrogen and an increase in cardiovascular and neurodegenerative disease risk. When studying the effects of menopause in mice, modeled by ovariectomy, it is important… read more here.
Keywords: function; soy free; ovx mice; physiology ... See more keywords
Wheel-Running Exercise Protects Ovariectomized Mice from Bone Loss via IFN-γ-Mediated Suppression of the NF-κB and MAPK Pathways
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/2030818
Abstract: Physical exercise is recommended as a preventative approach for osteoporosis; however, the effect of physical exercise on bone mass remains controversial. Additionally, the immune regulation of physical exercise on bone mass remains unclear. To determine… read more here.
Keywords: ovx mice; bone; mapk pathways; ifn ... See more keywords
Effects of Salvia miltiorrhiza extract with supplemental liquefied calcium on osteoporosis in calcium-deficient ovariectomized mice
Sign Up to like & getrecommendations! Published in 2017 at "BMC Complementary and Alternative Medicine"
DOI: 10.1186/s12906-017-2047-y
Abstract: BackgroundExtracts from Salvia miltiorrhiza Bunge have been used in traditional Asian medicine to treat coronary heart disease, chronic renal failure, atherosclerosis, myocardial infraction, angina pectoris, myocardial ischemia, dysmenorrheal, neurasthenic insomnia, liver fibrosis and cirrhosis. The… read more here.
Keywords: medicine; ovx mice; liquefied calcium; day ... See more keywords
8-Prenylgenistein, a prenylated genistein derivative, exerted tissue selective osteoprotective effects in ovariectomized mice
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.24823
Abstract: Our previous study reported that the in vitro osteogenic effects of 8-prenylgenistein (8PG) were more potent than its parent compound genistein. This study aimed to evaluate the osteoprotective effects of 8PG in ovariectomized (OVX) mice… read more here.
Keywords: genistein; bone; ovx mice; osteoprotective effects ... See more keywords
Polydatin alleviates osteoporosis by enhancing the osteogenic differentiation of osteoblasts.
Sign Up to like & getrecommendations! Published in 2022 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202206_29078
Abstract: OBJECTIVE: Osteoporosis is a severe degenerative chronic metabolic bone disease associated with high fracture risk. Polydatin (PD), a major bioactive component of Polygonum cuspidatum, has antioxidant and anti-inflammatory effects. This study investigated the anti-osteoporotic activity… read more here.
Keywords: ovx mice; alleviates osteoporosis; osteogenic differentiation; mice ... See more keywords
Cannabidiol-Treated Ovariectomized Mice Show Improved Glucose, Energy, and Bone Metabolism With a Bloom in Lactobacillus
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.900667
Abstract: Loss of ovarian 17β-estradiol (E2) in postmenopause is associated with gut dysbiosis, inflammation, and increased risk of cardiometabolic disease and osteoporosis. The risk-benefit profile of hormone replacement therapy is not favorable in postmenopausal women therefore… read more here.
Keywords: treated ovx; cbd; ovx mice; bone ... See more keywords
Progesterone Has No Impact on the Beneficial Effects of Estradiol Treatment in High-Fat-Fed Ovariectomized Mice
Sign Up to like & getrecommendations! Published in 2023 at "Current Issues in Molecular Biology"
DOI: 10.3390/cimb45050253
Abstract: In recent decades, clinical and experimental studies have revealed that estradiol contributes enormously to glycemic homeostasis. However, the same consensus does not exist in women during menopause who undergo replacement with progesterone or conjugated estradiol… read more here.
Keywords: replacement; ovx mice; high fat; mice treated ... See more keywords
Kefir Peptides Prevent Estrogen Deficiency-Induced Bone Loss and Modulate the Structure of the Gut Microbiota in Ovariectomized Mice
Sign Up to like & getrecommendations! Published in 2020 at "Nutrients"
DOI: 10.3390/nu12113432
Abstract: Osteoporosis is a major skeletal disease associated with estrogen deficiency in postmenopausal women. Kefir-fermented peptides (KPs) are bioactive peptides with health-promoting benefits that are produced from the degradation of dairy milk proteins by the probiotic… read more here.
Keywords: microbiota; gut microbiota; mice; ovx mice ... See more keywords