SIRT1/Notch1 signal axis involves in the promoting effect of Segetalin B on bone formation
Sign Up to like & getrecommendations! Published in 2022 at "Drug Development Research"
DOI: 10.1002/ddr.22001
Abstract: Phytoestrogens are a class of potential natural medicines for treating postmenopausal osteoporosis (PMOP). Segetalin B (SB) is a cyclic peptide compound showing estrogenic activity. This study reports the effect of SB on bone formation among… read more here.
Keywords: bone formation; ovx rats; effect; bone ... See more keywords
Protective effect of rhaponticin on ovariectomy‐induced osteoporosis in rats
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22837
Abstract: Rhaponticin is a constituent isolated from numerous medicinal herbs. It has been reported earlier that rhaponticin possesses numerous biological effects like antiallergic, antidiabetic, hepatoprotective, and antithrombosis. The goal of this exploration was to scrutinize the… read more here.
Keywords: ovx; osteoporosis rats; rhaponticin; rhaponticin ovariectomy ... See more keywords
Swimming improves cognitive reserve in ovariectomized rats and enhances neuroprotection after global cerebral ischemia
Sign Up to like & getrecommendations! Published in 2018 at "Brain Research"
DOI: 10.1016/j.brainres.2018.05.020
Abstract: Cognitive reserve has been proposed to account for different responses to brain damage or pathology. Factors implicated to influence cognitive reserve include cognitive engagement, physical activity, leisure activities, stress levels, and diet. Furthermore, long-term ovariectomy… read more here.
Keywords: swimming improves; brain; ischemia; ovx rats ... See more keywords
Estradiol and selective estrogen receptor agonists differentially affect brain monoamines and amino acids levels in transitional and surgical menopausal rat models
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2019.110533
Abstract: Estrogens have many beneficial effects in the brain. Previously, we evaluated the effects of two models of menopause (surgical vs. transitional) on multiple monoaminergic endpoints in different regions of the adult rat brain in comparison… read more here.
Keywords: estrogen receptor; agonist treatments; amino acids; estradiol selective ... See more keywords
Bioavailability of Isoflavone Metabolites After Korean Fermented Soybean Paste (Doenjang) Ingestion in Estrogen-Deficient Rats.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of food science"
DOI: 10.1111/1750-3841.14214
Abstract: Doenjang (DJ), a fermented soybean product used in soups, stews, and sauces, contains high quality proteins, fats, vitamins, minerals, and other functional ingredients, including isoflavones and saponins. This study investigated whether DJ improves the bioavailability… read more here.
Keywords: bioavailability; isoflavone; isoflavone metabolites; ovx rats ... See more keywords
A polysaccharide from the dried rhizome of Drynaria fortunei (Kunze) J. Sm. prevents ovariectomized (OVX)‐induced osteoporosis in rats
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.15072
Abstract: In the present study, a homogenous polysaccharide (DFPW) was isolated and purified from the dried rhizome of Drynaria fortunei, and its protective effect against osteoporosis was investigated in ovariectomized (OVX) rats. Histological analysis indicated that… read more here.
Keywords: drynaria fortunei; rhizome drynaria; dried rhizome; ovx rats ... See more keywords
17-B estradiol ameliorates oxidative stress, inflammation and apoptosis in the heart and aorta of ovariectomized Sprague Dawley rat model of collagen induced rheumatoid arthritis (CIA)
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5734865
Abstract: Menopause and rheumatoid arthritis (RA) are both known to cause elevation of blood Pressure in women, and it is known that RA is more prevalent in women around menopausal age. However, the mechanism of elevated… read more here.
Keywords: ovx rats; apoptosis; physiology; heart ... See more keywords
The Role of Epoxyeicosatrienoic Acids in Diabetes Mellitus-Induced Impaired Vascular Relaxation of Aortic Rings in Ovariectomized Sprague-Dawley Rats
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Endocrinology"
DOI: 10.1155/2019/5410108
Abstract: Aim The present study was aimed at determining if type 1 diabetes mellitus (DM) affects vascular function and at elucidating the mechanisms mediating vasorelaxation in both nonovariectomized and ovariectomized Sprague-Dawley (SD) rats. Materials and Methods… read more here.
Keywords: ovx; ovx ctr; diabetes mellitus; ovx rats ... See more keywords
Fructus Ligustri Lucidi modulates estrogen receptor expression with no uterotrophic effect in ovariectomized rats
Sign Up to like & getrecommendations! Published in 2018 at "BMC Complementary and Alternative Medicine"
DOI: 10.1186/s12906-018-2171-3
Abstract: BackgroundAccumulating evidence suggests that Fructus Ligustri Lucidi (FLL) plays a beneficial role in preventing the development of osteoporosis. However, the effects of FLL on estrogen receptor (ER) α and ERβ expressions remain unknown. Therefore, in… read more here.
Keywords: expression; fructus ligustri; ligustri lucidi; ovx rats ... See more keywords
Salivary microbiota of periodontitis aggravates bone loss in ovariectomized rats
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.983608
Abstract: The mechanisms underlying the crosstalk between periodontitis and osteoporosis remain unclear. Recently, the gut microbiota has been recognized as a pivotal regulator of bone metabolism, and oral and gut mucosae are microbiologically connected. In this… read more here.
Keywords: ovx rats; microbiota; bone loss; periodontitis ... See more keywords
Melatonin Accelerates Osteoporotic Bone Defect Repair by Promoting Osteogenesis–Angiogenesis Coupling
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.826660
Abstract: Previous studies have revealed that melatonin could play a role in anti-osteoporosis and promoting osteogenesis. However, the effects of melatonin treatment on osteoporotic bone defect and the mechanism underlying the effects of melatonin on angiogenesis… read more here.
Keywords: ovx rats; bone; osteoporotic bone; bone defect ... See more keywords