LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "oxa" as a keyword



PEGylated PAMAM dendrimers loading oxaliplatin with prolonged release and high payload without burst effect.

Sign Up to like & get
recommendations! Published in 2019 at "Biopolymers"

DOI: 10.1002/bip.23272

Abstract: Oxaliplatin (OXA) was coupled to PEGylated polyamidoamine dendrimers of fourth generation (G4-PEG@OXA) in the comparison to PEGylated ones of odd generation (G3.5-PEG@OXA). Proton nuclear magnetic resonance and Fourier-transform infrared spectroscopy were used to confirm the… read more here.

Keywords: peg oxa; oxa; oxaliplatin; pegylated pamam ... See more keywords

Rechallenge with oxaliplatin and peripheral neuropathy in colorectal cancer patients

Sign Up to like & get
recommendations! Published in 2018 at "Journal of Cancer Research and Clinical Oncology"

DOI: 10.1007/s00432-018-2691-8

Abstract: BackgroundOxaliplatin (OXA) is a cornerstone in the treatment of colorectal cancer (CRC). Retreatment with OXA is frequently considered as salvage treatment. OXA-induced neuropathy (OIN) is the most frequent and feared long-term side effect.Patients and methodsCRC… read more here.

Keywords: retreatment; colorectal cancer; cancer; oxa based ... See more keywords

The hypothalamic neuropeptide orexin A- a possible regulator in glucose homeostasis and germ cell kinetics in adult mice testes.

Sign Up to like & get
recommendations! Published in 2018 at "Biochimie"

DOI: 10.1016/j.biochi.2018.06.021

Abstract: Orexin A (OXA), a hypothalamic neuropeptide, regulates food intake, sleep-wake cycle and energy balance by binding to its receptor (OX1R). Apart from brain, OXA and OX1R are also present in peripheral organs including reproductive tissues.… read more here.

Keywords: glucose homeostasis; oxa ox1r; adult mice; germ cell ... See more keywords

Oxacillin promotes membrane vesicle secretion in Staphylococcus aureus via a SarA-Sle1 regulatory cascade.

Sign Up to like & get
recommendations! Published in 2024 at "Nanoscale"

DOI: 10.1039/d4nr04321a

Abstract: Membrane vesicles (MVs) are nanoscale particles secreted by living bacteria in vitro and in vivo. Bacterial MVs encapsulate various proteins, making them promising candidates for developing vaccines, drug carriers, and cancer immunotherapy agents. However, the… read more here.

Keywords: aureus; mvs; sle1; secretion ... See more keywords
Photo from wikipedia

Novel hyaluronic acid oligosaccharide-loaded and CD44v6-targeting oxaliplatin nanoparticles for the treatment of colorectal cancer

Sign Up to like & get
recommendations! Published in 2021 at "Drug Delivery"

DOI: 10.1080/10717544.2021.1914777

Abstract: Abstract Oxaliplatin resistance is one of the main causes of failed colorectal cancer treatment, followed by recurrence and metastasis. In this study, we found that colorectal cancer cells secrete a high level of hyaluronic acid… read more here.

Keywords: oha lipid; cd44v6; lipid oxa; colorectal cancer ... See more keywords

Prevalence of a New Variant OXA-204 and OXA-48 Carbapenemases Plasmids Encoded in Klebsiella pneumoniae Clinical Isolates in Tunisia

Sign Up to like & get
recommendations! Published in 2017 at "Microbial Drug Resistance"

DOI: 10.1089/mdr.2016.0236

Abstract: Carbapenemase-producing Klebsiella pneumoniae strains have emerged as a major problem for healthcare systems. The aim of this study was to determine the role and diversity of plasmids harboring carbapenemases encoding genes from a collection of… read more here.

Keywords: pneumoniae; klebsiella pneumoniae; new variant; prevalence new ... See more keywords

Colonization with Enterobacteriaceae-Producing ESBLs, AmpCs, and OXA-48 in Wild Avian Species, Spain 2015-2016.

Sign Up to like & get
recommendations! Published in 2018 at "Microbial drug resistance"

DOI: 10.1089/mdr.2018.0004

Abstract: Antibiotic resistance is a global threat of complex and changeable epidemiology. The role of wild birds in the dissemination of antibacterial resistance might be underestimated. We studied the cloacal colonization by cefotaxime-resistant Enterobacteriaceae in 668… read more here.

Keywords: cefotaxime resistant; colonization enterobacteriaceae; colonization; wild birds ... See more keywords

PCR Detection of Oxacillinases in Bacteria.

Sign Up to like & get
recommendations! Published in 2020 at "Microbial drug resistance"

DOI: 10.1089/mdr.2019.0330

Abstract: Oxacillinases (OXA) have been mostly described in Enterobacteriaceae, Acinetobacter, and Pseudomonas species. Recent years have witnessed an increased prevalence of intrinsic and/or acquired β-lactamase-producing Acinetobacter in food-producing animals. This study was conducted to assess the… read more here.

Keywords: oxacillinases bacteria; presence; pcr detection; detection oxacillinases ... See more keywords

Deciphering the role of residues in the loops nearing the active site of OXA-58 in imparting beta-lactamase activity.

Sign Up to like & get
recommendations! Published in 2022 at "Microbiology"

DOI: 10.1099/mic.0.001203

Abstract: The existence of OXA-58 carbapenemase alone or in combination with other beta-lactam resistance factors poses significant beta-lactam resistance. The exact mechanism of action of OXA type beta-lactamases is debatable due to the involvement of multiple… read more here.

Keywords: role residues; oxa; activity; active site ... See more keywords

Structural Insights into the Mechanism of Carbapenemase Activity of the OXA-48 β-Lactamase

Sign Up to like & get
recommendations! Published in 2019 at "Antimicrobial Agents and Chemotherapy"

DOI: 10.1128/aac.01202-19

Abstract: Carbapenem-hydrolyzing class D carbapenemases (CHDLs) are enzymes that produce resistance to the last-resort carbapenem antibiotics, severely compromising the available therapeutic options for the treatment of life-threatening infections. A broad variety of CHDLs, including OXA-23, OXA-24/40,… read more here.

Keywords: baumannii; mechanism carbapenemase; oxa; carbapenemase activity ... See more keywords

Clinical evaluation of advanced MALDI-TOF MS for carbapenemase subtyping in Gram-negative isolates

Sign Up to like & get
recommendations! Published in 2024 at "Journal of Clinical Microbiology"

DOI: 10.1128/jcm.01475-24

Abstract: ABSTRACT The spread of carbapenemase-producing Enterobacterales (CPE) is emerging as a significant clinical concern in tertiary hospitals and, in particular, long-term care facilities with deficiencies in infection control. This study aims to evaluate an advanced… read more here.

Keywords: carbapenemase; mass; kpc ndm; ndm oxa ... See more keywords