Three cases of OXA-48-like carbapenemase producing Enterobacteriaceae (not) detected using Xpert® Carba-R
Sign Up to like & getrecommendations! Published in 2017 at "Acta Clinica Belgica"
DOI: 10.1080/17843286.2016.1198520
Abstract: The increasing prevalence of carbapenemase-producing Enterobacteriaceae necessitates laboratories to invest in the detection of these bacteria, both with phenotypic and to a lesser extent molecular methods. OXA-48-like strains are rapidly emerging, especially in Europe. Since… read more here.
Keywords: carbapenemase producing; cases oxa; producing enterobacteriaceae; three cases ... See more keywords
OXA-48-like carbapenemases in the UK: an analysis of isolates and cases from 2007 to 2014
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkx012
Abstract: Objectives OXA-48-like carbapenemases have spread worldwide since 2001. We analysed patient and microbiological data for UK isolates with these enzymes as confirmed by the national reference laboratory from November 2007 to December 2014. Methods MICs… read more here.
Keywords: carbapenemases analysis; bla oxa; like carbapenemases; oxa like ... See more keywords
Predominant Distribution of OXA-48-Like Carbapenemase in Fecal Colonization
Sign Up to like & getrecommendations! Published in 2020 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00189-20
Abstract: Carbapenem-resistant Enterobacteriaceae (CRE) has become a public health threat worldwide.…. read more here.
Keywords: oxa like; distribution oxa; predominant distribution; like carbapenemase ... See more keywords
OXA-48-Like-Producing Klebsiella pneumoniae in Southern Spain in 2014–2015
Sign Up to like & getrecommendations! Published in 2018 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01396-18
Abstract: The aim of this study was to characterize the population structure of 56 OXA-48-like-producing Klebsiella pneumoniae isolates, as well as extended-spectrum β-lactamase (ESBL) and carbapenemase genes, recovered in 2014 and 2015 from 16 hospitals in… read more here.
Keywords: producing klebsiella; like producing; oxa like; klebsiella pneumoniae ... See more keywords
Performance of disk diffusion, gradient test, and VITEK 2 for carbapenem susceptibility testing in OXA-48-like carbapenemase-producing Enterobacterales: a comparative study
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.01893-24
Abstract: ABSTRACT This study aimed to compare the performance of disk diffusion, gradient test (ETEST), and VITEK 2 (AST-N223, AST-N428, AST-N432 cards) antibiotic susceptibility testing methods with the reference broth microdilution (BMD) for carbapenem susceptibility in… read more here.
Keywords: susceptibility testing; susceptibility; vitek; performance ... See more keywords
In vitro activity of ceftazidime–avibactam and comparators against OXA-48-like Enterobacterales collected between 2016 and 2020
Sign Up to like & getrecommendations! Published in 2024 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.01473-23
Abstract: ABSTRACT Oxacillinases (OXA)-48-like β-lactamases are one of the most common resistance determinants among carbapenem-resistant Enterobacterales reported globally. Moreover, there is no standard treatment available against organisms producing OXA-48-like enzymes, and they are sometimes difficult to… read more here.
Keywords: treatment; caz avi; blaoxa like; resistance ... See more keywords
Evaluation of the SpeeDx Carba (beta) multiplex real-time PCR assay for detection of NDM, KPC, OXA-48-like, IMP-4-like and VIM carbapenemase genes
Sign Up to like & getrecommendations! Published in 2019 at "BMC Infectious Diseases"
DOI: 10.1186/s12879-019-4176-z
Abstract: BackgroundCarbapenemase-producing organisms (CPOs) have emerged as antibiotic-resistant bacteria of global concern. Here we assessed the performance of the Carba (beta) assay, a multiplex real-time PCR assay developed by SpeeDx for the detection of key carbapenemase-encoding… read more here.
Keywords: carba beta; beta assay; carbapenemase; oxa like ... See more keywords
Bloodstream infections caused by multidrug-resistant gram-negative bacteria: epidemiological, clinical and microbiological features
Sign Up to like & getrecommendations! Published in 2019 at "BMC Infectious Diseases"
DOI: 10.1186/s12879-019-4265-z
Abstract: BackgroundBloodstream infections (BSI) are associated with high morbidity and mortality. This scenario worsens with the emergence of drug-resistant pathogens, resulting in infections which are difficult to treat or even untreatable with conventional antimicrobials. The aim… read more here.
Keywords: infections caused; gram negative; gram; resistance ... See more keywords
Carbapenem resistance in critically important human pathogens isolated from companion animals: a systematic literature review
Sign Up to like & getrecommendations! Published in 2022 at "Osong Public Health and Research Perspectives"
DOI: 10.24171/j.phrp.2022.0033
Abstract: This study aimed to describe the presence and geographical distribution of Gram-negative bacteria considered critical on the priority list of antibiotic-resistant pathogens published by the World Health Organization, including carbapenem-resistant Enterobacteriaceae, carbapenem-resistant Acinetobacter spp., and… read more here.
Keywords: carbapenem resistant; review; important human; oxa like ... See more keywords
Comparative genomic analysis of plasmids harboring bla OXA-48-like genes in Klebsiella pneumoniae
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.1082813
Abstract: The emergence and spread of carbapenem-resistant Klebsiella pneumoniae (CRKP) is a serious medical problem worldwide. Acquired OXA-48-like carbapenemases encoded by plasmids are important causes of carbapenem resistance in K. pneumoniae. To explore the links between… read more here.
Keywords: klebsiella pneumoniae; oxa like; bla; like genes ... See more keywords
Evaluation of the Immunochromatographic NG-Test Carba 5, RESIST-5 O.O.K.N.V., and IMP K-SeT for Rapid Detection of KPC-, NDM-, IMP-, VIM-type, and OXA-48-like Carbapenemase Among Enterobacterales
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2020.609856
Abstract: Background Enterobacterales are the most common pathogens for nosocomial infections. The emergence and spread of KPC, NDM, and OXA-48-like carbapenemase-producing Enterobacterales with their extensively drug-resistant characteristics have posed great threats to public health. This study… read more here.
Keywords: imp; imp set; carba resist; test carba ... See more keywords