Oxa-Nazarov Cyclization-Michael Addition Sequence for the Rapid Construction of Dihydrofuranones.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03601
Abstract: The Nazarov cyclization has been established as a powerful tool in constructing cyclopentenone skeletons. In sharp contrast, oxa-Nazarov cyclization that affords dihydrofuranones, a new type of product, has been less explored. In this work, we… read more here.
Keywords: nazarov cyclization; oxa nazarov; michael addition; cyclization ... See more keywords
Asymmetric binary-acid catalysis: a diastereo- and enantioselective oxa-Nazarov cyclization-Michael addition of conjugated 1,2-diketones
Sign Up to like & getrecommendations! Published in 2023 at "Organic Chemistry Frontiers"
DOI: 10.1039/d3qo00558e
Abstract: Diastereo- and enantioselective oxa-Nazarov cyclization-Michael addition of conjugated 1,2-diketones was achieved by using an asymmetric binary-acid catalysis with chiral phosphoric acid and FeBr3. The reaction affords the corresponding chiral 3(2H)-furanones... read more here.
Keywords: nazarov cyclization; enantioselective oxa; diastereo enantioselective; oxa nazarov ... See more keywords