Comparative Kinetic Analysis of OXA-438 with related OXA-48-Type Carbapenem-Hydrolyzing Class D β-Lactamases.
Sign Up to like & getrecommendations! Published in 2020 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.0c00537
Abstract: Novel variants of the OXA-48 type enzymes with the ability to hydrolyze oxyimino-cephalosporins and carbapenems, are increasingly reported. Since its first report in 2011, OXA-163 is now extensively spread in Argentina and several variants like… read more here.
Keywords: oxyimino cephalosporins; oxa 438; oxa 163; oxa 247 ... See more keywords
The C5α-Methyl-Substituted Carbapenem NA-1-157 Exhibits Potent Activity against Klebsiella spp. Isolates Producing OXA-48-Type Carbapenemases.
Sign Up to like & getrecommendations! Published in 2023 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.3c00059
Abstract: The wide spread of carbapenem-hydrolyzing β-lactamases in Gram-negative bacteria has diminished the utility of the last-resort carbapenem antibiotics, significantly narrowing the available therapeutic options. In the Enterobacteriaceae family, which includes many important clinical pathogens such… read more here.
Keywords: substituted carbapenem; oxa type; methyl substituted; producing oxa ... See more keywords