Target Identification of an Antimalarial Oxaborole Identifies AN13762 as an Alternative Chemotype for Targeting CPSF3 in Apicomplexan Parasites
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DOI: 10.1016/j.isci.2020.101871
Abstract: Summary Boron-containing compounds represent a promising class of molecules with proven efficacy against a wide range of pathogens, including apicomplexan parasites. Following lead optimization, the benzoxaborole AN13762 was identified as a preclinical candidate against the… read more here.
Keywords: identification antimalarial; oxaborole identifies; target identification; identifies an13762 ... See more keywords