Synthesis of benzimidazole-linked-1,3,4-oxadiazole carboxamides as GSK-3β inhibitors with in vivo antidepressant activity.
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DOI: 10.1016/j.bioorg.2018.01.040
Abstract: Recent findings of potential implications of glycogen synthase kinase-3β (GSK-3β) dysfunction in psychiatric disorders like depression, have increased focus for development of GSK-3β inhibitors with possible anti-depressant activity. Keeping this in view, we synthesized a… read more here.
Keywords: oxadiazole carboxamides; linked oxadiazole; benzimidazole linked; vivo antidepressant ... See more keywords