Innovative Pyrazole–Thiazole–Oxadiazole Hybrid Compounds for Targeted EGFR/VEGFR2 Inhibition in Cancer Treatment
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DOI: 10.1002/ardp.70122
Abstract: A new series of pyrazole–thiazole–oxadiazole hybrid compounds targeting the EGFR and VEGFR2 enzymes was designed and synthesized using innovative approaches. The compounds were characterized through spectral methods, and their cytotoxic activities were evaluated against the… read more here.
Keywords: cancer; pyrazole thiazole; inhibition; oxadiazole hybrid ... See more keywords
Cholyl 1,3,4-oxadiazole hybrid compounds: design, synthesis and antimicrobial assessment
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DOI: 10.3762/bjoc.18.63
Abstract: A new chemical library based on the hybridization of cholic acid with the heterocyclic moiety 1,3,4-oxadizole was synthesized, and tested for antimicrobial activity against Gram-positive, Gram-negative bacteria, and fungi. Among the synthesized compounds, the most… read more here.
Keywords: design synthesis; cholyl oxadiazole; oxadiazole hybrid; hybrid compounds ... See more keywords