Articles with "oxadiazole quinazoline" as a keyword



Design and synthesis of new 1,2,4-oxadiazole/quinazoline-4-one hybrids with antiproliferative activity as multitargeted inhibitors

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Published in 2024 at "Frontiers in Chemistry"

DOI: 10.3389/fchem.2024.1447618

Abstract: Introduction The combination of BRAF and tyrosine kinase (TK) inhibitors has been demonstrated to be highly effective in inhibiting tumor development and is an approach for overcoming resistance in clinical trials. Accordingly, a novel series… read more here.

Keywords: one hybrids; oxadiazole quinazoline; antiproliferative agents; quinazoline one ... See more keywords