A convenient route to the 1,2,5-oxadiazole-substituted 1,2,4-triazolo[1,5-a]pyrimidine derivatives
Sign Up to like & getrecommendations! Published in 2019 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-019-02590-7
Abstract: A convenient synthesis of 1,2,4-triazole and 1,2,4-triazolo[1,5-a]pyrimidines with 3-amino-1,2,5-oxadiazole substituent starting from available 4-amino-1,2,5-oxadiazole-3-carbohydrazide and benzoyl cyanamide has been developed. read more here.
Keywords: route oxadiazole; triazolo pyrimidine; pyrimidine derivatives; substituted triazolo ... See more keywords
Oxadiazole-substituted naphtho[2,3-b]thiophene-4,9-diones as potent inhibitors of keratinocyte hyperproliferation. Structure-activity relationships of the tricyclic quinone skeleton and the oxadiazole substituent.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.03.084
Abstract: Novel analogues of oxadiazole-substituted naphtho[2,3-b]thiophene-4,9-diones were synthesized in which the tricyclic quinone skeleton was systematically replaced with simpler moieties, such as structures with fewer rings and open-chain forms, while the oxadiazole ring was maintained. In… read more here.
Keywords: hyperproliferation; naphtho thiophene; substituted naphtho; tricyclic quinone ... See more keywords