Synthesis, anti‐inflammatory activity, and molecular docking studies of some novel Mannich bases of the 1,3,4‐oxadiazole‐2(3H)‐thione scaffold
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DOI: 10.1002/ardp.202000061
Abstract: A series of novel ibuprofen and salicylic acid‐based 3,5‐disubstituted‐1,3,4‐oxadiazole‐2(3H)‐thione derivatives was synthesized, and they were evaluated as potential anti‐inflammatory agents. Following the structure identification studies employing IR, 1H nuclear magnetic resonance (NMR), 13C NMR, and… read more here.
Keywords: anti inflammatory; docking studies; oxadiazole thione; synthesis anti ... See more keywords
Synthesis and Antimicrobial Activity of 1,3,4‐Oxadiazole‐2(3H)‐thione and Azidomethanone Derivatives Based on Quinoline‐4‐carbohydrazide Derivatives
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DOI: 10.1002/jhet.2529
Abstract: A new series compounds of quinoline derivatives were synthesized by reaction of 3-(carboxymethyl)-2-arylquinoline-4-carboxylic acids 1a, 1b, 1c with different nucleophiles. The structures of the new compounds were elucidated on the basis of FTIR, 1H-NMR, 13C-NMR… read more here.
Keywords: antimicrobial activity; oxadiazole thione; activity oxadiazole; synthesis antimicrobial ... See more keywords
Syntheses, spectral and structural characterization of Cd(II) complexes of 5-(thiophen-2-yl)-1,3,4-oxadiazole-2-thione, 2-thiohydantoin and 2-thenoyltrifluoroacetone
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DOI: 10.1016/j.poly.2017.05.012
Abstract: Abstract Three Cd(II) complexes, [Cd(5-thot)2(en)2] (1), [Cd(thd)2(µ-Br)]n (2) and [Cd(ttfa)2(en)] (3) have been synthesized from 5-(thiophen-2-yl)-1,3,4-oxadiazole-2-thione, 2-thiohydantoin and 2-thenoyltrifluoroacetone by the reaction of cadmium(II) salt. The complexes have been characterized by various physicochemical methods. Complexes… read more here.
Keywords: oxadiazole thione; thione; geometry; thiophen oxadiazole ... See more keywords