Short-term Safety, Tolerability, and Pharmacokinetics of MRX-I, an Oxazolidinone Antibacterial Agent, in Healthy Chinese Subjects.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical therapeutics"
DOI: 10.1016/j.clinthera.2017.12.017
Abstract: PURPOSE This study was designed to evaluate the safety and pharmacokinetic profiles of MRX-I tablet, an oxazolidinone antibacterial agent, in healthy Chinese subjects. METHODS The study was composed of 3 sequential periods. Period 1 was… read more here.
Keywords: healthy chinese; study; oxazolidinone antibacterial; chinese subjects ... See more keywords
Current Landscape and Future Perspective of Oxazolidinone Scaffolds Containing Antibacterial Drugs.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c00480
Abstract: The widespread use of antibiotics has made the problem of bacterial resistance increasingly serious, and the study of new drug-resistant bacteria has become the main direction of antibacterial drug research. Among antibiotics, the fully synthetic… read more here.
Keywords: antibacterial drugs; landscape future; oxazolidinone antibacterial; future perspective ... See more keywords