Synthesis and SARS-CoV-2 3CL Protease Inhibitory Effects of Oxazolidinone Derivatives
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DOI: 10.21577/0103-5053.20220033
Abstract: The 3-chymotrypsin-like protease (3CLpro) is an attractive target for the development of anti- SARS (severe acute respiratory syndrome) drugs. In this work, a series of oxazolidinone derivatives 3a-3v were synthesized and their inhibitory activities against… read more here.
Keywords: protease inhibitory; sars cov; synthesis sars; 3cl protease ... See more keywords
Biologically Active 2-oxazolidinone Derivatives beyond Antibacterial Activities.
Sign Up to like & getrecommendations! Published in 2022 at "Current medicinal chemistry"
DOI: 10.2174/0929867329666220823113415
Abstract: 2-oxazolidinone is well known as a pharmacophore for antibacterial agents represented by two marketed medicines, Linezolid and Tedizolid. On the other hand, there are growing reports on the various biological activities of 2-oxazolidinones beyond antibacterial… read more here.
Keywords: beyond antibacterial; active oxazolidinone; oxazolidinone derivatives; antibacterial activities ... See more keywords