Straightforward Access To Block And Gradient Light-Responsive Poly(2-Oxazoline)S Via Cationic Ring Opening Polymerization Of 2-Azobenzenyl-2-Oxazoline.
Sign Up to like & getrecommendations! Published in 2023 at "Macromolecular rapid communications"
DOI: 10.1002/marc.202300032
Abstract: Light-responsive polymers are a prospective area of smart materials. The increasing number of potential applications of these materials requires the development of new polymers sensitive to external irradiation. However, most of the polymers reported so… read more here.
Keywords: light responsive; oxazoline; poly oxazoline; block ... See more keywords
Block Length-Dependent Protein Fouling on Poly(2-oxazoline)-Based Polymersomes: Influence on Macrophage Association and Circulation Behavior.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202201993
Abstract: Polymersomes are vesicular structures self-assembled from amphiphilic block copolymers and are considered an alternative to liposomes for applications in drug delivery, immunotherapy, biosensing, and as nanoreactors and artificial organelles. However, the limited availability of systematic… read more here.
Keywords: protein fouling; circulation; poly oxazoline; block ... See more keywords
Co-delivery of paclitaxel and cisplatin in poly(2-oxazoline) polymeric micelles: Implications for drug loading, release, pharmacokinetics and outcome of ovarian and breast cancer treatments.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2018.10.032
Abstract: Concurrent delivery of multiple drugs using nanoformulations can improve outcomes of cancer treatments. Here we demonstrate that this approach can be used to improve the paclitaxel (PTX) and alkylated cisplatin prodrug combination therapy of ovarian… read more here.
Keywords: oxazoline; drug; ovarian breast; breast cancer ... See more keywords
Poly(2-oxazoline)-based micro- and nanoparticles: A review
Sign Up to like & getrecommendations! Published in 2017 at "European Polymer Journal"
DOI: 10.1016/j.eurpolymj.2016.09.011
Abstract: Abstract Poly(2-oxazoline)s (POx) are a class of polymers with tremendous potential for biomedical applications. The straightforward access to side and main chain functionalities by selecting suitable monomers and initiators/terminating agents, respectively, in combination with the… read more here.
Keywords: micro nanoparticles; poly oxazoline; oxazoline based; oxazoline ... See more keywords
Probing the Biocompatibility and Immune Cell Association of Chiral, Water-Soluble, Bottlebrush Poly(2-oxazoline)s.
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c01105
Abstract: Poly(2-oxazoline)s (POx) have received substantial attention as poly(ethylene glycol) (PEG) alternatives in the biomedical field due to their biocompatibility, high functionality, and ease of synthesis. While POx have demonstrated strong potential as biomaterial constituents, the… read more here.
Keywords: immune cell; biocompatibility; poly; association ... See more keywords
Poly(2-oxazoline)-Pterostilbene Block Copolymer Nanoparticles for Dual-Anticancer Drug Delivery.
Sign Up to like & getrecommendations! Published in 2018 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.7b01279
Abstract: Functional block copolymers based on poly(2-oxazoline)s are versatile building blocks for the fabrication of dual-drug delivery nanoparticles (NPs) for anticancer chemotherapy. Core-shell NPs are fabricated from diblock copolymers featuring a long and hydrophilic poly(2-methyl-2-oxazoline) (PMOXA) block… read more here.
Keywords: drug delivery; poly oxazoline; block; oxazoline ... See more keywords
How To Tune the Gene Delivery and Biocompatibility of Poly(2-(4-aminobutyl)-2-oxazoline) by Self- and Coassembly.
Sign Up to like & getrecommendations! Published in 2018 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.7b01535
Abstract: Despite their promising potential in gene transfection, the toxicity and limited efficiency of cationic polymers as nonviral vectors are major obstacles for their broader application. The large amount of cationic charges, for example, in poly(ethylene… read more here.
Keywords: transfection; biocompatibility; oxazoline; tune gene ... See more keywords
Degradable Poly(2-oxazoline) Analogues from Partially Oxidized Poly(ethylene imine)
Sign Up to like & getrecommendations! Published in 2020 at "Macromolecules"
DOI: 10.1021/acs.macromol.0c02143
Abstract: A series of degradable poly(2-n-alkyl-2-oxazoline-stat-glycine)s was synthesized in a modular manner via a straightforward postpolymerization synthesis route comprising consecutive hydrolysis of po... read more here.
Keywords: analogues partially; poly oxazoline; partially oxidized; oxazoline ... See more keywords
Mixing Poly(ethylene glycol) and Poly(2-alkyl-2-oxazoline)s Enhances Hydration and Viscoelasticity of Polymer Brushes and Determines Their Nanotribological and Antifouling Properties.
Sign Up to like & getrecommendations! Published in 2018 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.8b17193
Abstract: Poly(2-alkyl-2-oxazoline)s (PAOXAs) have progressively emerged as suitable alternatives for replacing poly(ethylene glycol) (PEG) in a variety of biomaterial-related applications, especially in the designing of polymer brush-based biointerfaces because of their stealth properties and chemical robustness.… read more here.
Keywords: alkyl oxazoline; poly alkyl; polymer; oxazoline ... See more keywords
Synthesis and Structure–Property Relationship of Amphiphilic Poly(2-ethyl-co-2-(alkyl/aryl)-2-oxazoline) Copolymers
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c04809
Abstract: Poly(2-oxazoline)s (POZs) are widely investigated for their applications in various fields due to their unique properties. To exploit and combine different characteristics of the POZ family, 2-oxazoline monomers can be copolymerized to prepare tailor-made copolymers… read more here.
Keywords: synthesis structure; side chains; molecular weight; side ... See more keywords
The effect of linker length on ConA and DC-SIGN binding of S-glucosyl functionalized poly(2-oxazoline)s
Sign Up to like & getrecommendations! Published in 2018 at "Polymer Chemistry"
DOI: 10.1039/c7py01939d
Abstract: A new monomer, 2-[2-(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosylthio) propyl)]-2-oxazoline (Ac4Glc-S-Ox), was synthesized by direct addition of 2,3,4,6-Tetra-O-acetyl-1-thio-β-D-glucopyranose (Ac4Glc-SH) to 2-Isopropenyl-2-oxazoline (iPOx) in the presence of solid butyl amine resin via thiol-ene click reaction. The living cationic ring-opening polymerization was… read more here.
Keywords: effect linker; linker; linker length; oxazoline ... See more keywords