Population pharmacokinetics of oxcarbazepine and its metabolite 10‐hydroxycarbazepine in healthy subjects
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2017.05.034
Abstract: Abstract Oxcarbazepine is indicated for the treatment of partial or generalised tonic‐clonic seizures. Most of the absorbed oxcarbazepine is converted into its active metabolite, 10‐hydroxycarbazepine (MHD), which can exist as R‐(−)‐ and S‐(+)‐MHD enantiomers. Here… read more here.
Keywords: mhd enantiomers; oxcarbazepine; healthy subjects; metabolite hydroxycarbazepine ... See more keywords
The role of reactive oxygen species and carbonate radical in oxcarbazepine degradation via UV, UV/H2O2: Kinetics, mechanisms and toxicity evaluation.
Sign Up to like & getrecommendations! Published in 2018 at "Water research"
DOI: 10.1016/j.watres.2018.10.007
Abstract: Oxcarbazepine (OXC) is ubiquitous in the aqueous environment. And due to its ecotoxicological effects and potential risks to human, an effective way to eliminate OXC from aqueous environment has aroused public concerns in recent years.… read more here.
Keywords: oxygen; degradation; oxc degradation; degradation via ... See more keywords
Pimavanserin for bipolar disorder
Sign Up to like & getrecommendations! Published in 2022 at "Bipolar Disorders"
DOI: 10.1111/bdi.13191
Abstract: Table 1 summarizes the key characteristics of the three patients with bipolar illness. Figure 1 provides a partial life chart of patient 1 over the time that she has been diagnosed with Parkinson’s disease; the… read more here.
Keywords: function; oxcarbazepine; pimavanserin bipolar; patient ... See more keywords
Hepatitis C-related cryoglobulinemic neuropathy: potential role of oxcarbazepine for pain control
Sign Up to like & getrecommendations! Published in 2018 at "BMC Gastroenterology"
DOI: 10.1186/s12876-018-0751-9
Abstract: BackgroundPeripheral neuropathy is one most common, limiting and invalidating neurological symptom in subjects with hepatitis C virus and mixed cryoglobulinemia. Notably, the medical therapy proposed to eradicate HCV, can frequently exacerbate the painful neuropathy. Therefore,… read more here.
Keywords: hepatitis related; cryoglobulinemic neuropathy; related cryoglobulinemic; oxcarbazepine ... See more keywords