Asymmetric Synthesis of Pyrrolidines via Oxetane Desymmetrization.
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DOI: 10.1021/acs.orglett.2c00564
Abstract: Asymmetric synthesis of chiral pyrrolidines bearing an all-carbon quaternary stereocenter in the 3-position remains challenging. Herein we report two efficient protocols by means of oxetane desymmetrization, featuring the use of a readily available tert-butylsulfinamide chiral… read more here.
Keywords: pyrrolidines via; oxetane desymmetrization; asymmetric synthesis; synthesis pyrrolidines ... See more keywords