Oxidant-induced increase in norepinephrine secretion from PC12 cells is dependent on TRPM8 channel-mediated intracellular calcium elevation.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.10.120
Abstract: Reactive oxygen species (ROS) modulate neuronal function, including plasticity and neurotransmitter biosynthesis and release. The cellular mechanisms that underlie redox modulation of neurotransmission are not fully resolved, but potential pathways include ROS-induced alterations in Ca2+… read more here.
Keywords: trpm8 channel; oxidant induced; pc12 cells; norepinephrine secretion ... See more keywords
Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical biology"
DOI: 10.1021/acschembio.2c00740
Abstract: Chemical proteomics is a powerful technology that can be used in the studies of the functions of uncharacterized proteins in the human proteome. It relies on a suitable bioconjugation strategy for protein labeling. This could… read more here.
Keywords: protein labeling; bioconjugation protein; induced bioconjugation; bioconjugation ... See more keywords