Structure–activity relationships of fraxamoside as an unusual xanthine oxidase inhibitor
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DOI: 10.1080/14756366.2016.1252758
Abstract: Abstract Fraxamoside, a macrocyclic secoiridoid glucoside featuring a hydroxytyrosol group, was recently identified as a xanthine oxidase inhibitor (XOI) comparable in potency in vitro to the standard antigout drug allopurinol. However, this activity and its… read more here.
Keywords: xanthine oxidase; activity relationships; oxidase inhibitor; structure activity ... See more keywords
The Xanthine Oxidase Inhibitor Febuxostat Suppresses Adipogenesis and Activates Nrf2
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DOI: 10.3390/antiox12010133
Abstract: Xanthine oxidoreductase (XOR) is a rate-limiting enzyme in purine catabolism that acts as a novel regulator of adipogenesis. In pathological states, xanthine oxidoreductase activity increases to produce excess reactive oxygen species (ROS). The nuclear factor… read more here.
Keywords: adipogenesis; xanthine oxidase; oxidase inhibitor; febuxostat ... See more keywords
More Than a Diamine Oxidase Inhibitor: L-Aminoguanidine Modulates Polyamine-Related Abiotic Stress Responses of Plants
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DOI: 10.3390/life13030747
Abstract: L-aminoguanidine (AG) is an inhibitor frequently used for investigating plant abiotic stress responses; however, its exact mode of action is not well understood. Many studies used this compound as a specific diamine oxidase inhibitor, whereas… read more here.
Keywords: oxidase inhibitor; diamine oxidase; inhibitor; abiotic stress ... See more keywords
Anti-diabetic effect of a monoamine oxidase inhibitor (tranylcypromine) in rats with poorly-controlled blood glucose levels: A potential and novel therapeutic option for diabetes
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DOI: 10.4314/tjpr.v19i6.20
Abstract: Purpose: To determine the anti-diabetic effect of a monoamine oxidase inhibitor (tranylcypromine) in sulphonyl urea-refractory rats with poorly-controlled blood glucose levels. Methods: Alloxan-induced diabetic Wistar rats were assigned to two groups (30 rats/group). One group… read more here.
Keywords: inhibitor tranylcypromine; oxidase inhibitor; blood; monoamine oxidase ... See more keywords