Anti-metastatic Inhibitors of Lysyl Oxidase (LOX): Design and Structure–Activity Relationships
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DOI: 10.1021/acs.jmedchem.9b00335
Abstract: Lysyl oxidase (LOX) is a secreted copper-dependent amine oxidase that cross-links collagens and elastin in the extracellular matrix and is a critical mediator of tumor growth and metastatic spread. LOX is a target for cancer… read more here.
Keywords: chemistry; lox; lysyl oxidase; structure activity ... See more keywords