Climbing the Oxidase Phase Ladder by Using Dioxygen as the Sole Oxidant: The Case Study of Costunolide
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DOI: 10.1021/acs.orglett.4c00406
Abstract: Natural sesquiterpenoid lactones are prominent scaffolds in drug discovery. Despite the progress made in their synthesis, their extensive oxidative decoration makes their chemo- and stereoselective syntheses highly challenging. Herein, we report our effort to mimic… read more here.
Keywords: using dioxygen; sole oxidant; dioxygen sole; oxidase phase ... See more keywords