Myocardial inflammation is associated with impaired mitochondrial oxidative capacity in ischaemic cardiomyopathy
Sign Up to like & getrecommendations! Published in 2024 at "ESC Heart Failure"
DOI: 10.1002/ehf2.15133
Abstract: Myocardial inflammation and impaired mitochondrial oxidative capacity are hallmarks of heart failure (HF) pathophysiology. The extent of myocardial inflammation in patients suffering from ischaemic cardiomyopathy (ICM) or dilated cardiomyopathy (DCM) and its association with mitochondrial… read more here.
Keywords: ischaemic cardiomyopathy; myocardial inflammation; oxidative capacity; inflammation ... See more keywords
Capillary rarefaction during bed rest is proportionally less than fibre atrophy and loss of oxidative capacity
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13072
Abstract: Muscle disuse from bed rest or spaceflight results in losses in muscle mass, strength and oxidative capacity. Capillary rarefaction may contribute to muscle atrophy and the reduction in oxidative capacity during bed rest. Artificial gravity… read more here.
Keywords: oxidative capacity; capillary rarefaction; bed rest; atrophy ... See more keywords
One-leg inactivity induces a reduction in mitochondrial oxidative capacity, intramyocellular lipid accumulation and reduced insulin signalling upon lipid infusion: a human study with unilateral limb suspension
Sign Up to like & getrecommendations! Published in 2020 at "Diabetologia"
DOI: 10.1007/s00125-020-05128-1
Abstract: Aims/hypothesis Physical inactivity, low mitochondrial function, increased intramyocellular lipid (IMCL) deposition and reduced insulin sensitivity are common denominators of chronic metabolic disorders, like obesity and type 2 diabetes. Yet, whether low mitochondrial function predisposes to… read more here.
Keywords: insulin; oxidative capacity; mitochondrial oxidative; leg ... See more keywords
Methodological considerations on near-infrared spectroscopy derived muscle oxidative capacity
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Applied Physiology"
DOI: 10.1007/s00421-024-05421-6
Abstract: Different strategies for near-infrared spectroscopy (NIRS)-derived muscle oxidative capacity assessment have been reported. This study compared and evaluated (I) approaches for averaging trials; (II) NIRS signals and blood volume correction equations; (III) the assessment of… read more here.
Keywords: spectroscopy; oxidative capacity; derived muscle; muscle oxidative ... See more keywords
Effects of dietary chromium yeast and astaxanthin on the growth performance, anti-oxidative capacity, and resistance to heat stress of abalone Haliotis discus hannai
Sign Up to like & getrecommendations! Published in 2021 at "Aquaculture International"
DOI: 10.1007/s10499-021-00656-y
Abstract: This study was aimed at evaluating whether dietary chromium yeast (CrYst) and astaxanthin (ASTA) could enhance the growth performance, anti-oxidative capacity, and resistance to heat stress of abalone Haliotis discus hannai (initial body weight: 1.14±0.10… read more here.
Keywords: heat stress; cryst; oxidative capacity; anti oxidative ... See more keywords
Experimental models of lipid overload and their relevance in understanding skeletal muscle insulin resistance and pathological changes in mitochondrial oxidative capacity.
Sign Up to like & getrecommendations! Published in 2021 at "Biochimie"
DOI: 10.1016/j.biochi.2021.09.010
Abstract: It remains essential to decipher some of the pathological mechanisms that link obesity with deteriorating human health. Insulin resistance, due to enhanced free fatty acid substrate delivery, results in disrupted glucose homeostasis and altered mitochondrial… read more here.
Keywords: insulin; oxidative capacity; mitochondrial oxidative; lipid overload ... See more keywords
Oxidative Capacity Storage of Transient Singlet Oxygen from Photosensitization with a Redox Mediator for Improved Chemiluminescent Sensing.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b01675
Abstract: Singlet oxygen, generated from type-II photosensitization, becomes increasing popular in bioassay developments in recent years. However, the transient nature of singlet oxygen in water (lifetime shorter than 4 μs) as well as its high activity… read more here.
Keywords: oxygen; oxidative capacity; photosensitization; redox ... See more keywords
Higher skeletal muscle mitochondrial oxidative capacity is associated with preserved brain structure up to over a decade
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-55009-z
Abstract: Impaired muscle mitochondrial oxidative capacity is associated with future cognitive impairment, and higher levels of PET and blood biomarkers of Alzheimer’s disease and neurodegeneration. Here, we examine its associations with up to over a decade-long… read more here.
Keywords: spectroscopy; brain; muscle; oxidative capacity ... See more keywords
Mild hyperbaric oxygen inhibits the growth‐related decline in skeletal muscle oxidative capacity and prevents hyperglycemia in rats with type 2 diabetes mellitus
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Diabetes"
DOI: 10.1111/1753-0407.12666
Abstract: Humans and animals with type 2 diabetes mellitus (T2DM) exhibit low skeletal muscle oxidative capacity and impaired glucose metabolism. The aim of the present study was to investigate the effects of exposure to mild hyperbaric… read more here.
Keywords: skeletal muscle; mild hyperbaric; oxidative capacity; muscle oxidative ... See more keywords
Diffusion and physical constraints limit oxidative capacity, capillary supply and size of muscle fibres in mice and humans.
Sign Up to like & getrecommendations! Published in 2025 at "Experimental physiology"
DOI: 10.1113/ep092750
Abstract: It has been suggested that angiogenesis during skeletal muscle fibre hypertrophy allows escape from the ‘size constraint’, which is the inverse relationship between oxidative capacity and muscle fibre cross‐sectional area (FCSA). It is, however, not… read more here.
Keywords: capacity; muscle; oxidative capacity; capillary supply ... See more keywords
Maximal-effort knee-extension exercise impairs skeletal muscle oxidative capacity and VO2 recovery in vivo.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of applied physiology"
DOI: 10.1152/japplphysiol.00517.2025
Abstract: In the present study, we examined how fatiguing exercise affects O2-based measures of skeletal muscle oxidative capacity in vivo by measuring changes in the rate constant of muscle VO2 recovery (kVO2). Healthy young adults completed… read more here.
Keywords: skeletal muscle; muscle; oxidative capacity; vo2 ... See more keywords