Neuroprotective potency of a soy whey fermented by Cordyceps militaris SN-18 against hydrogen peroxide-induced oxidative injury in PC12 cells
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Nutrition"
DOI: 10.1007/s00394-021-02679-w
Abstract: Soy whey is a byproduct generated from the processing of several soybean products. Its valorization has continued to attract significant research interest in recent times due to the nutritional and bioactive potency of its chemical… read more here.
Keywords: soy whey; soy; oxidative injury; pc12 cells ... See more keywords
Gualou Guizhi Granule Protects Against Oxidative Injury by Activating Nrf2/ARE Pathway in Rats and PC12 Cells
Sign Up to like & getrecommendations! Published in 2018 at "Neurochemical Research"
DOI: 10.1007/s11064-018-2507-x
Abstract: Stroke involves numerous pathophysiological processes and oxidative stress is considered as a main cellular event in its pathogenesis. The nuclear factor erythroid-2-related factor 2 (Nrf2)/antioxidant response element (ARE) pathway plays a key role in inducing… read more here.
Keywords: nrf2 pathway; oxidative injury; guizhi granule; gualou guizhi ... See more keywords
iKeap1 activates Nrf2 signaling to protect myocardial cells from oxygen glucose deprivation/re-oxygenation-induced oxidative injury.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.08.024
Abstract: Nuclear factor E2-related factor 2 (Nrf2) activation could efficiently protect myocardial cells from oxygen glucose deprivation/re-oxygenation (OGDR). An ultra-large structure-based virtual screening has discovered iKeap1 as a novel, direct and potent Keap1 inhibitor. Here we… read more here.
Keywords: induced oxidative; nrf2 signaling; myocardial cells; protect myocardial ... See more keywords
Autophagy inhibition attenuates hyperoxaluria-induced renal tubular oxidative injury and calcium oxalate crystal depositions in the rat kidney
Sign Up to like & getrecommendations! Published in 2018 at "Redox Biology"
DOI: 10.1016/j.redox.2018.03.019
Abstract: Hyperoxaluria-induced oxidative injury of renal tubular epithelial cell is a casual and essential factor in kidney calcium oxalate (CaOx) stone formation. Autophagy has been shown to be critical for the regulation of oxidative stress-induced renal… read more here.
Keywords: oxalate; hyperoxaluria induced; renal tubular; oxidative injury ... See more keywords
Gentamycin Rationally Repositioned to Inhibit miR-34a Ameliorates Oxidative Injury to PC12 Cells
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c06112
Abstract: Ischemic stroke accompanies oxidative stress and cell death in the cerebral tissue. The microRNA miR-34a plays a pivotal role in this molecular pathology. This study presents the rational repositioning of aminoglycosidic antibiotics as miR-34a antagonists… read more here.
Keywords: gentamycin; mir 34a; pc12 cells; oxidative injury ... See more keywords
CircMED12L Protects Against Hydrogen Peroxide-induced Apoptotic and Oxidative Injury in Human Lens Epithelial Cells by miR-34a-5p/ALCAM axis
Sign Up to like & getrecommendations! Published in 2022 at "Current Eye Research"
DOI: 10.1080/02713683.2022.2134427
Abstract: Abstract Purpose Cataract is the leading cause of visual impairment and reversible blindness. Despite advances in surgical removal of cataracts, cataract continues to be a leading public-health issue due to the complications after surgery. Circular… read more here.
Keywords: apoptotic oxidative; h2o2 induced; oxidative injury; circmed12l ... See more keywords
Acute and non-resolving inflammation associate with oxidative injury after human spinal cord injury
Sign Up to like & getrecommendations! Published in 2021 at "Brain"
DOI: 10.1093/brain/awaa360
Abstract: In spinal cord injury, the initial mechanical insult may be followed by progressive cord atrophy and neurodegeneration. Zrzavy et al. characterize innate and adaptive inflammatory responses in human spinal cord injury, and show that oxidative… read more here.
Keywords: cord; oxidative injury; human spinal; injury ... See more keywords
Metformin protects trabecular meshwork against oxidative injury via activating integrin/ROCK signals
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.06.30.498232
Abstract: Background This study aimed to investigate the protective effect of metformin on the trabecular meshwork (TM) and explore its molecular mechanisms in vivo and in vitro. Methods Ocular hypertension (OHT) mouse models were induced with… read more here.
Keywords: integrin rock; rock; rock signals; oxidative injury ... See more keywords
Nasturtium Officinale L. hydroalcoholic extract improved oxymetholone‐induced oxidative injury in mouse testis and sperm parameters
Sign Up to like & getrecommendations! Published in 2019 at "Andrologia"
DOI: 10.1111/and.13294
Abstract: Testicular tissue and sex hormones are sensitive to the anabolic steroids (oxymetholone/OM) due to increased free radical damage and hormonal changes. The Nasturtium officinale L. have various antioxidant compounds. The aim of the present study… read more here.
Keywords: testis; nasturtium officinale; induced oxidative; sperm parameters ... See more keywords
Centella asiatica alleviates diabetes‐induced changes in fatty acid profile and oxidative damage in rat testis
Sign Up to like & getrecommendations! Published in 2020 at "Andrologia"
DOI: 10.1111/and.13751
Abstract: The in vivo effects of Centella asiatica L. Urban (Family: Apiaceae; CA) on diabetes‐induced testicular fatty acid misdistribution and oxidative injury were investigated. Diabetic rats were treated with vehicle, CA or metformin daily for 14… read more here.
Keywords: testis; fatty acid; diabetic controls; centella asiatica ... See more keywords
Downregulation of CIRP Prone Cells to Oxidative Injury via Regulating Nrf2 Signaling Pathway
Sign Up to like & getrecommendations! Published in 2022 at "BioMed Research International"
DOI: 10.1155/2022/2416787
Abstract: Cold-inducible RNA-binding protein (CIRP) is a cellular stress-response protein, whose expression can be induced by a variety of stress conditions. Our previous study showed that intracellular CIRP is a protective factor against cellular oxidative stress… read more here.
Keywords: prone cells; signaling pathway; nrf2 signaling; oxidative injury ... See more keywords