Changes in oxidative RNA and DNA modifications following one-week treatment with sevelamer: two randomized, placebo-controlled trials
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.10.288
Abstract: Introduction Sevelamer is a phosphate-binding drug used in the treatment of chronic kidney disease. Studies have shown that sevelamer reduces oxidative stress measured as 8-isoprostanes. Oxidative RNA modifications are associated with increased cardiovascular as well… read more here.
Keywords: sevelamer; treatment sevelamer; treatment; oxidative rna ... See more keywords
Oxidative RNA Damage in the Pathogenesis and Treatment of Type 2 Diabetes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.725919
Abstract: Excessive production of free radicals can induce cellular damage, which is associated with many diseases. RNA is more susceptible to oxidative damage than DNA due to its single-stranded structure, and lack of protective proteins. Yet,… read more here.
Keywords: rna damage; damage; oxidative rna; rna ... See more keywords