Novel and facile synthesis of 1-benzazepines via copper-catalyzed oxidative C(sp3)-H/C(sp2)-H cross-coupling.
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DOI: 10.1039/c7cc07027f
Abstract: A novel and facile synthetic strategy for the construction of 1-benzazepines has been developed via copper-catalyzed oxidative C(sp3)-H/C(sp2)-H cross-coupling directly from two inert C-H bonds. This transformation represents an atom- and step-economical way to synthesize… read more here.
Keywords: oxidative sp3; copper catalyzed; via copper; sp3 sp2 ... See more keywords
Oxidative C(sp3)–H amidation of tertiary arylamines with nitriles
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DOI: 10.1039/c8qo00794b
Abstract: The first amidation of tertiary arylamines with nitriles via a cascade dehydrogenation/heterocoupling/addition reaction between α-C–H bonds of tertiary amines and nitrogen atoms of nitriles has been developed. The use of copper(I) iodide as a Lewis… read more here.
Keywords: oxidative sp3; amidation tertiary; tertiary arylamines; sp3 amidation ... See more keywords
Silver(i)-mediated oxidative C(sp3)–H amination of ethers with azole derivatives under mild conditions
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DOI: 10.1039/c9qo00644c
Abstract: A silver(i)-mediated oxidative N–H/C(sp3)–H coupling of NH-azoles with ethers has been developed. read more here.
Keywords: amination ethers; oxidative sp3; sp3 amination; silver mediated ... See more keywords