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   Articles with "oxidative stress" as a keyword



Oxidative Stress-Induced Damage to RNA and DNA and Mortality in Individuals with Psychiatric Illness.

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recommendations! Published in 2024 at "JAMA psychiatry"

DOI: 10.1001/jamapsychiatry.2024.0052

Abstract: Importance All-cause mortality and the risk for age-related medical disease is increased in individuals with psychiatric illness, but the underlying biological mechanisms are not known. Oxidative stress on nucleic acids (DNA and RNA; NA-OXS) is… read more here.

Keywords: history; illness; mortality; oxidative stress ... See more keywords

A shift in chromatin binding of phosphorylated p38 precedes transcriptional changes upon oxidative stress

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recommendations! Published in 2024 at "Febs Letters"

DOI: 10.1002/1873-3468.15006

Abstract: P38 mitogen‐activated protein kinases are key in the regulation of the cellular response to stressors. P38 is known to regulate transcription, mRNA processing, stability, and translation. The transcriptional changes mediated by phosphorylated p38 (P‐p38) in… read more here.

Keywords: phosphorylated p38; transcriptional changes; chromatin; oxidative stress ... See more keywords

Investigation of oxidative‐stress‐induced axon beading using photo‐oxidation

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recommendations! Published in 2025 at "FEBS Letters"

DOI: 10.1002/1873-3468.70074

Abstract: Oxidative stress caused by excessive reactive oxygen species adversely affects cellular function. Here, we investigate axonal beading induced by the photo‐oxidation of a membrane‐based fluorescent dye. Our experiments show that, apart from using oxygen scavengers,… read more here.

Keywords: stress; oxidative stress; axon beading; stress induced ... See more keywords

Inhibition of glycolysis disrupts cellular antioxidant defense and sensitizes HepG2 cells to doxorubicin treatment

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recommendations! Published in 2019 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12628

Abstract: Increased glucose consumption is a known hallmark of cancer cells. Increased glycolysis provides ATP, reducing agents and substrates for macromolecular synthesis in intensely dividing cells. Therefore, inhibition of glycolysis is one strategy in anticancer therapy… read more here.

Keywords: inhibition glycolysis; glycolysis; hepg2 cells; antioxidant defense ... See more keywords

Blueberry juice protects osteocytes and bone precursor cells against oxidative stress partly through SIRT1

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recommendations! Published in 2019 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12634

Abstract: Oxidative stress and abnormal osteocyte apoptosis are often related to dysregulation of bone turnover and chronic bone loss, and so fruit and vegetables with high antioxidant potential may play an important role in the prevention… read more here.

Keywords: blueberry juice; bone; oxidative stress;

XBP1 inhibits mesangial cell apoptosis in response to oxidative stress via the PTEN/AKT pathway in diabetic nephropathy

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recommendations! Published in 2019 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12655

Abstract: Diabetic nephropathy (DN) is a complication of diabetes mellitus (DM) that frequently results in renal disease, and is characterized by a variety of symptoms, including albuminuria. It has been shown that apoptosis of glomerular mesangial… read more here.

Keywords: pten akt; apoptosis; oxidative stress; cell apoptosis ... See more keywords

Analogs of imine resveratrol alleviate oxidative stress‐induced neurotoxicity in PC12 cells via activation of Nrf2

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recommendations! Published in 2021 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13209

Abstract: Oxidative stress is closely associated with neurodegenerative, cardiovascular and metabolic diseases. Resveratrol and related compounds have shown great potential as antioxidants via either direct scavenging of abundant reactive oxygen species (ROS) or activation of the… read more here.

Keywords: resveratrol; pc12 cells; imine resveratrol; activation ... See more keywords

Obesity‐induced oxidative stress and mitochondrial dysfunction negatively affect sperm quality

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recommendations! Published in 2023 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13589

Abstract: Obesity is a systemic metabolic disease that can induce male infertility or subfertility through oxidative stress. The aim of this study was to determine how obesity impairs sperm mitochondrial structural integrity and function, and reduces… read more here.

Keywords: obesity; sperm quality; stress; oxidative stress ... See more keywords

Oxidative stress in the tumor microenvironment in gastric cancer and its potential role in immunotherapy.

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recommendations! Published in 2023 at "FEBS open bio"

DOI: 10.1002/2211-5463.13630

Abstract: Gastric cancer (GC) is the fourth leading cause of cancer-related death and the fifth most common malignant tumor globally. However, the clinical efficacy of conventional therapies is limited. Currently, immunotherapy is considered an effective therapeutic… read more here.

Keywords: oxidative stress; cancer; tumor microenvironment; gastric cancer ... See more keywords

Selective Twin NIR‐IIb Ratiometric Luminescence Nanoprobes Enable the Accurate Visualization of MPO‐Mediated Oxidative Stress in Acute Liver Injury

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recommendations! Published in 2024 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202414772

Abstract: Oxidative stress, orchestrated by myeloperoxidase (MPO), plays crucial roles in the progression of many diseases. Nonetheless, the role of MPO‐mediated oxidative stress in distinct factor‐induced acute liver injuries (ALI) is still up for dispute, mainly… read more here.

Keywords: mediated oxidative; mpo mediated; oxidative stress; iib ... See more keywords

Spatiotemporal Regulation of Oxidative Stress by Redox Relays for Ischemia‐Reperfusion Injury Rescue

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recommendations! Published in 2025 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202513467

Abstract: Effective therapeutic strategies for ischemiareperfusion injury (IRI) remain elusive. Targeting reactive oxygen species (ROS) provides a practical approach to mitigate tissue damage following reperfusion. However, antioxidant mediated management of IRI is greatly hampered by the… read more here.

Keywords: redox; reperfusion; stress; oxidative stress ... See more keywords