High levels of oxidatively generated DNA damage 8,5'-cyclo-2'-deoxyadenosine accumulate in the brain tissues of xeroderma pigmentosum group A gene-knockout mice.
Sign Up to like & getrecommendations! Published in 2019 at "DNA repair"
DOI: 10.1016/j.dnarep.2019.04.004
Abstract: Xeroderma pigmentosum (XP) is a genetic disorder associated with defects in nucleotide excision repair, a pathway that eliminates a wide variety of helix-distorting DNA lesions, including ultraviolet-induced pyrimidine dimers. In addition to skin diseases in… read more here.
Keywords: oxidatively generated; group gene; cyclo; xeroderma pigmentosum ... See more keywords
Differential time responses in inflammatory and oxidative stress markers after a marathon: An observational study
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DOI: 10.1080/02640414.2020.1770918
Abstract: ABSTRACT Acute and adaptive changes in systemic markers of oxidatively generated nucleic acid modifications (i.e., 8-oxo-7,8-dihydro-2สน-deoxyguanosine (8-oxodG) and 8-oxo-7,8-dihydroguanosine (8-oxoGuo)) as well as inflammatory cytokines (i.e., C-reactive protein, interleukin-6, interleukin-10, and tumour necrosis factor alpha),… read more here.
Keywords: excretion; study; acid modifications; generated nucleic ... See more keywords
Hydroxyl radical is predominantly involved in oxidatively generated base damage to cellular DNA exposed to ionizing radiation
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DOI: 10.1080/09553002.2022.2067363
Abstract: Jean Cadet , Dimitar Angelov and J. Richard Wagner D epartement de M edecine Nucl eaire et Radiobiologie, Facult e de M edecine, Universit e de Sherbrooke, Sherbrooke, Canada; Laboratoire de Biologie et de Mod… read more here.
Keywords: radical predominantly; hydroxyl radical; involved oxidatively; oxidatively generated ... See more keywords