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Published in 2023 at "Molecular oncology"
DOI: 10.1002/1878-0261.13419
Abstract: Human epidermal growth factor receptor 2 (ErbB2/HER2) is a tyrosine kinase receptor that is overexpressed in 25% of primary human breast cancers, as well as in multiple other cancers. HER2-targeted therapies improved progression-free and overall…
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Keywords:
ebselen oxide;
oxide derivatives;
her2;
new allosteric ... See more keywords
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Published in 2021 at "Journal of Molecular Modeling"
DOI: 10.1007/s00894-021-04911-0
Abstract: The (3 + 2) cycloaddition (32CA) reaction is an efficient method for the synthesis of many biologically active heterocyclic compounds, but there are several regio- and stereochemical issues that must be fully understood to exploit the full…
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Keywords:
nitrile oxide;
usepackage;
methylene pyrrolidinone;
oxide derivatives ... See more keywords
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Published in 2019 at "Coordination Chemistry Reviews"
DOI: 10.1016/j.ccr.2019.06.011
Abstract: Abstract Organic derivatives of nitric oxide can serve as ligands for transition metals in a variety of fashions. This review surveys recent developments in the coordination chemistry of four main classes of organic NO derivatives:…
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Keywords:
coordination chemistry;
oxide derivatives;
organic nitric;
nitric oxide ... See more keywords
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Published in 2019 at "Annales pharmaceutiques francaises"
DOI: 10.1016/j.pharma.2018.11.004
Abstract: OBJECTIVES This work aims at getting more insights into the distinct behavior of S-oxide derivatives of thiocarbonyl-containing antitubercular drugs, in order to better understand their mechanism of action and toxicity. METHODS Computational calculation of relative…
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Keywords:
antitubercular drugs;
action toxicity;
sulfenic acid;
oxide derivatives ... See more keywords
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1
Published in 2019 at "Molecules"
DOI: 10.3390/molecules24132348
Abstract: Infections caused by Fasciola species are widely distributed in cattle and sheep causing significant economic losses, and are emerging as human zoonosis with increasing reports of human cases, especially in children in endemic areas. The…
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Keywords:
quinoxaline oxide;
activity liver;
oxide derivatives;
inhibitors activity ... See more keywords