Partially Oxidized Alginate as a Biodegradable Carrier for Glucose‐Responsive Insulin Delivery and Islet Cell Replacement Therapy
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DOI: 10.1002/adhm.202201822
Abstract: Self‐regulated insulin delivery that mimics native pancreas function has been a long‐term goal for diabetes therapies. Two approaches towards this goal are glucose‐responsive insulin delivery and islet cell transplantation therapy. Here, biodegradable, partially oxidized alginate… read more here.
Keywords: cell; oxidized alginate; insulin delivery; glucose responsive ... See more keywords
Characterization of an oxidized alginate-gelatin hydrogel incorporating a COS-salicylic acid conjugate for wound healing.
Sign Up to like & getrecommendations! Published in 2021 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2020.117145
Abstract: In the present study, chitooligosaccharide (COS) and salicylic acid (SA) conjugates were synthesized using H2O2-induced grafting polymerization and oxidized alginate (OA) and gelatin hydrogels were fabricated using Schiff's base reaction. To confirm the synthesis and… read more here.
Keywords: wound healing; gelatin; oxidized alginate; cos salicylic ... See more keywords
3D Bioprinting of carbohydrazide-modified gelatin into microparticle-suspended oxidized alginate for fabrication of complex-shaped tissue constructs.
Sign Up to like & getrecommendations! Published in 2020 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.0c05096
Abstract: Extrusion-based bioprinting of hydrogels in a granular secondary gel enables the fabrication of cell-laden three-dimensional (3D) constructs in an anatomically accurate manner, which is challenging using conventional extrusion-based bioprinting processes. In this study, carbohydrazide-modified gelatin… read more here.
Keywords: modified gelatin; gel cdh; suspended oxidized; oxidized alginate ... See more keywords
Oxidized Alginate Dopamine Conjugate: In Vitro Characterization for Nose-to-Brain Delivery Application
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DOI: 10.3390/ma14133495
Abstract: Background: The blood–brain barrier (BBB) bypass of dopamine (DA) is still a challenge for supplying it to the neurons of Substantia Nigra mainly affected by Parkinson disease. DA prodrugs have been studied to cross the… read more here.
Keywords: nose brain; brain delivery; oxidized alginate; alginate dopamine ... See more keywords
Electroactive Oxidized Alginate/Gelatin/MXene (Ti3C2Tx) Composite Hydrogel with Improved Biocompatibility and Self-Healing Property
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DOI: 10.3390/polym14183908
Abstract: Conductive hydrogels (CHs) have shown promising potential applied as wearable or epidermal sensors owing to their mechanical adaptability and similarity to natural tissues. However, it remains a great challenge to develop an integrated hydrogel combining… read more here.
Keywords: alginate gelatin; self healing; oxidized alginate; property ... See more keywords