Identification and visualization of oxidized lipids in atherosclerotic plaques by microscopic imaging mass spectrometry-based metabolomics.
Sign Up to like & getrecommendations! Published in 2020 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2020.08.001
Abstract: BACKGROUND AND AIMS Dysregulated lipid metabolism has emerged as one of the major risk factors of atherosclerosis. Presently, there is a consensus that oxidized LDL (oxLDL) promotes development of atherosclerosis and downstream chronic inflammatory responses.… read more here.
Keywords: atherosclerotic plaques; mass spectrometry; microscopic imaging; oxidized lipids ... See more keywords
Oxidized lipids in atherosclerotic plaque instability
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.05.021
Abstract: A large body of evidence suggests a mechanistic link between oxidized lipids and atherosclerosis. Oxysterols and 4-hydroxynonenal (HNE), the major products deriving from LDL oxidation, are consistently present in inflamed and atherosclerotic arteries and they… read more here.
Keywords: oxidized lipids; plaque; oxysterols hne; plaque instability ... See more keywords
Structure Annotation and Quantification of Wheat Seed Oxidized Lipids by High-Resolution LC-MS/MS1[CC-BY]
Sign Up to like & getrecommendations! Published in 2017 at "Plant Physiology"
DOI: 10.1104/pp.17.00470
Abstract: Acyl composition annotation and quantification of hundreds of oxidized and nonoxidized lipids in naturally aged wheat seeds by high-resolution LC-MS/MS reveals enhanced lipid oxidation at ambient versus cold conditions. Lipid oxidation is a process ubiquitous… read more here.
Keywords: seed; high resolution; wheat; oxidized lipids ... See more keywords
Myeloid-cell derived oxidized lipids and regulation of the tumor microenvironment.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer research"
DOI: 10.1158/0008-5472.can-21-3054
Abstract: Immune suppressive myeloid cells play a major role in cancer by negatively regulating immune responses, promoting tumor progression, and limiting the efficacy of cancer immunotherapy. Immune suppression is mediated by various mechanisms dependent upon the… read more here.
Keywords: myeloid; myeloid cell; cell derived; oxidized lipids ... See more keywords