E prostanoid receptor‐3 promotes oxidized low‐density lipoprotein‐induced human aortic smooth muscle cells inflammation
Sign Up to like & getrecommendations! Published in 2022 at "ESC Heart Failure"
DOI: 10.1002/ehf2.14264
Abstract: The progression of atherosclerosis can lead to the occurrence of multiple cardiovascular diseases (coronary heart disease, etc.). E prostanoid receptor‐3 (EP3) is known to participate in the progression of atherosclerosis. This study aimed to investigate… read more here.
Keywords: promotes oxidized; prostanoid receptor; receptor promotes; low density ... See more keywords
MiR‐182‐5p inhibited oxidative stress and apoptosis triggered by oxidized low‐density lipoprotein via targeting toll‐like receptor 4
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26389
Abstract: MicroRNAs (miRNAs) exhibit various roles in multiple biological processes and abnormal expression of miR‐182‐5p has been involved in many diseases. However, the role miR‐182‐5p in Atherosclerosis (AS) remains poorly understood. In our current investigation, an… read more here.
Keywords: toll like; oxidized low; apoptosis; mir 182 ... See more keywords
Oxidized low‐density lipoprotein suppresses mouse granulosa cell differentiation through disruption of the hypoxia‐inducible factor 1 pathway
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.22933
Abstract: Obesity predisposes women to reproductive disorders. One symptom of obesity in women is higher levels of oxidized Low‐density lipoprotein (oxLDL) in serum and preovulatory follicles. The present study was designed to test the hypothesis that… read more here.
Keywords: oxidized low; density lipoprotein; inducible factor; low density ... See more keywords
Gingival mesenchymal stem cells attenuate pro-inflammatory macrophages stimulated with oxidized low-density lipoprotein and modulate lipid metabolism.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2018.11.007
Abstract: OBJECTIVE To examine the effects of gingival mesenchymal stem cells (GMSCs) on inflammatory macrophages upon oxidized low-density lipoprotein (ox-LDL) stimulation and evaluate therapeutic potential of GMSCs on mouse model of periodontitis associated with hyperlipidemia. METHODS… read more here.
Keywords: oxidized low; density lipoprotein; gmscs; density ... See more keywords
Association of angiotensin II receptor 1 and lectin-like oxidized low-density lipoprotein receptor-1 mediates the cardiac hypertrophy induced by oxidized low-density lipoprotein.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.06.010
Abstract: To date the molecular mechanism of cardiac hypertrophy has not been completely elucidated. Since oxidized low-density lipoprotein (ox-LDL) is considered a risk marker for early ventricular remodeling, we speculated that ox-LDL may be related to… read more here.
Keywords: low density; oxidized low; density lipoprotein; cardiac hypertrophy ... See more keywords
Increased serum ferritin is associated with oxidized low-density lipoprotein in prediabetes patients: A pilot study
Sign Up to like & getrecommendations! Published in 2021 at "Heliyon"
DOI: 10.1016/j.heliyon.2021.e06720
Abstract: Aims This pilot study aimed to determine if increased serum ferritin (SF) is associated with cardiovascular risk factors in patients with prediabetes. Methods Eighteen patients with prediabetes and 36 subjects without prediabetes (control), non-white Hispanic,… read more here.
Keywords: oxidized low; pilot study; increased serum; ferritin associated ... See more keywords
Correlation between mechanism of oxidized-low density lipoprotein-induced macrophage apoptosis and inhibition of target gene platelet derived growth factor receptor-β expression by microRNA-9
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineered"
DOI: 10.1080/21655979.2021.2006864
Abstract: ABSTRACT This study was to explore the effects of oxidized-low density lipoprotein (ox-LDL) on the proliferation and apoptosis of macrophages, and the role of miRNA-9 in the targeted regulation of platelet-derived growth factor receptor-β (PDGFR-β)… read more here.
Keywords: expression; oxidized low; apoptosis; low density ... See more keywords
Circular RNA circCHFR downregulation protects against oxidized low-density lipoprotein-induced endothelial injury via regulation of microRNA-15b-5p/growth arrest and DNA damage inducible gamma
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2032967
Abstract: ABSTRACT Atherosclerosis is the leading cause of coronary heart disease. In recent years, circ_0029589 (circCHFR) has been found to be associated with atherosclerosis development. However, the molecular mechanism of circCHFR action in atherosclerosis development is… read more here.
Keywords: mir 15b; oxidized low; atherosclerosis; low density ... See more keywords
Nintedanib ameliorates oxidized low-density lipoprotein -induced inflammation and cellular senescence in vascular endothelial cells
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DOI: 10.1080/21655979.2022.2036913
Abstract: ABSTRACT Atherosclerosis (AS) is a life-threatening cardiovascular disease and it has been reported that endothelial dysfunction is the initial inducer of AS. Recent reports suggest that inflammation and oxidative stress-induced cell senescence are main inducers… read more here.
Keywords: inflammation; endothelial cells; senescence; low density ... See more keywords
Oxidized Low-Density Lipoproteins Induce Tissue Factor Expression in T-Lymphocytes via activation of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1.
Sign Up to like & getrecommendations! Published in 2019 at "Cardiovascular research"
DOI: 10.1093/cvr/cvz230
Abstract: BACKGROUND T-lymphocytes plays an important role in the pathophysiology of acute coronary syndromes (ACS). T-cell activation in vitro by pro-inflammatory cytokines may lead to functional Tissue Factor (TF) expression, indicating a possible contribution of immunity… read more here.
Keywords: oxidized low; lox; low density; expression ... See more keywords
Oxidized low‐density lipoprotein, lipid and calcium aggregates reveal oxidative stress and inflammation in the conjunctiva of glaucoma patients
Sign Up to like & getrecommendations! Published in 2017 at "Acta Ophthalmologica"
DOI: 10.1111/aos.13380
Abstract: Conjunctival specimens from primary open‐angle glaucoma (POAG), exfoliation glaucoma (ExG) patients and controls were histologically analysed for oxidized low‐density lipoprotein (ox‐LDL), lipid and calcium aggregates. Our goal was to use them as biomarkers of oxidative… read more here.
Keywords: oxidized low; density lipoprotein; calcium aggregates; glaucoma ... See more keywords